Active Metabolite
Lisdexamfetamine, Prodrug, Morphine-6-glucuronide
Herausgegeben: Cristóbal, Barnabas
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Please note that the content of this book primarily consists of articles available from Wikipedia or other free sources online. An active metabolite is an active form of a drug after it has been processed by the body.Sometimes drugs are formulated deliberately so they will break down inside the body to form the active drug, these are called prodrugs. The reason for this may be because the drug is more stable during manufacture and storage as the prodrug form, or because the prodrug is better absorbed by the body or has superior pharmacokinetics (e.g., lisdexamphetamine).Another kind of active ...
Please note that the content of this book primarily consists of articles available from Wikipedia or other free sources online. An active metabolite is an active form of a drug after it has been processed by the body.Sometimes drugs are formulated deliberately so they will break down inside the body to form the active drug, these are called prodrugs. The reason for this may be because the drug is more stable during manufacture and storage as the prodrug form, or because the prodrug is better absorbed by the body or has superior pharmacokinetics (e.g., lisdexamphetamine).Another kind of active metabolite is when a drug is broken down by the body into a modified form which continues to produce effects in the body. Usually these effects are similar to those of the parent drug but weaker, although they can still be significant (see e.g. 11-hydroxy-THC, morphine-6-glucuronide).
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