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Accelerated Partial Breast Irradiation
Techniques and Clinical Implementation
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Accelerated partial breast irradiation (APBI) is being rapidly introduced into the clinical management of early breast cancer. APBI, in fact, encompasses a number of different techniques and approaches that include brachytherapy, intraoperative, and external beam techniques. There is currently no single source that describes these techniques and their clinical implementation. This text will be a concise handbook designed to assist the clinician in the implementation of APBI. This will include a review of the principles that underlie APBI, a practical and detailed description of each technique ...
Accelerated partial breast irradiation (APBI) is being rapidly introduced into the clinical management of early breast cancer. APBI, in fact, encompasses a number of different techniques and approaches that include brachytherapy, intraoperative, and external beam techniques. There is currently no single source that describes these techniques and their clinical implementation. This text will be a concise handbook designed to assist the clinician in the implementation of APBI. This will include a review of the principles that underlie APBI, a practical and detailed description of each technique for APBI, a review of current clinical results of APBI, and a review of the incidence and management of treatment related complications.
Table of contents:
Background:APBI: history, rationale, and controversies.-Pathologic anatomy of breast cancer and relevance to APBI.-Who is a candidate for APBI?.-APBI: defining the target.-The radiobiology of APBI: dose, fractionation, and dose rate.-Techniques:Surgical considerations for APBI.-APBI: interstitial brachytherapy by CT guidance.-APBI: interstitial brachytherapy by rigid template.-APBI: interstitial brachytherapy by template and mammographic guidance.-APBI: mammosite.-APBI: 3-D conformal external beam.-APBI: intraoperative approaches.-APBI: a dosimetric and radiobiologic comparison of brachytherapy, external beam, and intraoperative techniques.-New technologies and novel approaches to APBI.-Physics quality assurance for APBI.-Clinical Results:APBI: review of clinical trials.-APBI: toxicity and acceptable normal tissue constraint.
Table of contents:
Background:APBI: history, rationale, and controversies.-Pathologic anatomy of breast cancer and relevance to APBI.-Who is a candidate for APBI?.-APBI: defining the target.-The radiobiology of APBI: dose, fractionation, and dose rate.-Techniques:Surgical considerations for APBI.-APBI: interstitial brachytherapy by CT guidance.-APBI: interstitial brachytherapy by rigid template.-APBI: interstitial brachytherapy by template and mammographic guidance.-APBI: mammosite.-APBI: 3-D conformal external beam.-APBI: intraoperative approaches.-APBI: a dosimetric and radiobiologic comparison of brachytherapy, external beam, and intraoperative techniques.-New technologies and novel approaches to APBI.-Physics quality assurance for APBI.-Clinical Results:APBI: review of clinical trials.-APBI: toxicity and acceptable normal tissue constraint.