A High Performance Algorithm For Prediction of Protein Interactions
Deducing potential protein-protein interactions in the light of existing data
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The major goal of Computational Biology and Bioinformatics is to achieve a better understanding of the principles of biological systems and processes using informatics tools. Elucidation of the full network of protein-protein interactions is a crucial part of this challenge. Thus, there is a growing need for fast and reliable in silico methods for predicting protein-protein interactions. Here, we present a high-performance algorithm for automated prediction of protein-protein interactions. We adopt a novel bottom-up approach that combines structure and sequence conservation in protein interfac...
The major goal of Computational Biology and Bioinformatics is to achieve a better understanding of the principles of biological systems and processes using informatics tools. Elucidation of the full network of protein-protein interactions is a crucial part of this challenge. Thus, there is a growing need for fast and reliable in silico methods for predicting protein-protein interactions. Here, we present a high-performance algorithm for automated prediction of protein-protein interactions. We adopt a novel bottom-up approach that combines structure and sequence conservation in protein interfaces.
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