Gebundenes Buch

¿-Carbolines

A Privileged Scaffold for Modern Drug Discovery

Herausgegeben: Ameta, Keshav Lalit
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beta-Carbolines: A Privileged Scaffold for Modern Drug Discovery provides a summary of methods for the synthesis of various natural products engineered with the diverse beta-carboline scaffold and their biological evaluation.beta-carboline and its derivatives have generated considerable interest in recent years for their versatile properties in chemistry and pharmacology. This is due to their ability to act as agonists to benzodiazepine receptors, hydroxy serotonin receptors, and intercalate into DNA and to inhibit CDK, topisomerase, and monoamine oxidase enzymes. Their pharmacological propert...