Oxidative Stress and Antioxidant Protection (eBook, PDF)

The Science of Free Radical Biology and Disease
Redaktion: Armstrong, Donald; Stratton, Robert D.

• Format: PDF

Produktbeschreibung

Oxidative Stress and Antioxidant Protection: The Science of Free Radical Biology and< Disease provides an overview of the basic principles of free radical formation. The text delves into free radical formation in molecular biology and its effect on subcellular damage, as well as the role of antioxidant reserves as a protective mechanism. Oxidative Stress and Antioxidant Protection begins with a historical perspective of pioneers in oxidative stress with an introductory section that explains the basic principles related to oxidative stress in biochemistry and molecular biology, demonstrating both pathways and biomarkers. This section also covers diagnostic imaging and differential diagnostics. The following section covers psychological, physiologic, pharmacologic and pathologic correlates. This section addresses inheritance, gender, nutrition, obesity, family history, behavior modification, natural herbal-botanical products, and supplementation in the treatment of disease. Clinical trials are also summarized for major medical disorders and efficacy of treatment, with particular focus on inflammation, immune response, recycling, disease progression, outcomes and interventions. Each of the chapters describes what biomarker(s) and physiological functions may be relevant to a concept of specific disease and potential alternative therapy. The chapters cover medical terminology, developmental change, effects of aging, senescence, lifespan, and wound healing, and also illustrates cross-over exposure to other fields. The final chapter covers how and when to interpret appropriate data used in entry level biostatistics and epidemiology. Authored and edited by leaders in the field, Oxidative Stress and Antioxidant Protection will be an invaluable resource for students and researchers studying cell biology, molecular biology, and biochemistry, as well professionals in various health science fields.

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Produktdetails

• Verlag: John Wiley & Sons
• Seitenzahl: 600
• Erscheinungstermin: 14. Januar 2016
• Englisch
• ISBN-13: 9781118832370
• Artikelnr.: 44503554

Autorenporträt

Donald Armstrong is an Emeritus Professor at the State University of New York at Buffalo in Buffalo, NY, USA, Courtesy Research Professor of Ophthalmology at the University of Florida College of Medicine in Gainesville, FL, USA, Visiting Professor of Ophthalmology at Showa University School of Medicine in Tokyo, Japan and Founder and CEO of?Oxidative Stress Associates, Inc. Robert D. Stratton is a retired physician and founder of?Erie Retinal Surgery, Inc., in Erie, PA.?He is also an Adjunct Professor at the University of Florida College of Medicine, Department of Animal Clinical Sciences and a Courtesy Assistant Professor in the Department of Ophthalmology at the University of Florida in Gainesville, FL, USA.

Inhaltsangabe

List of Contributors
ix Special Recognition
xiii Foreword
xv Preface
xvii Section 1: Introduction 1 Introduction to Free Radicals
Inflammation
and Recycling
3 Donald Armstrong 2 Diagnostic Imaging and Differential Diagnosis
11 Robert D. Stratton Section 2: Clinical Correlations on Acute and Chronic Diseases 3 Free Radicals: Their Role in Brain Function and Dysfunction
23 Natan Gadoth 4 Mediators of Neuroinflammation
39 Rajiv Tikamdas
Ping Zhang
and Bin Liu 5 Oxidative and Nitrative Stress in Schizophrenia
57 Anna Dietrich-Muszalska 6 The Effects of Hypoxia
Hyperoxia
and Oxygen Fluctuations on Oxidative Signaling in the Preterm Infant and on Retinopathy of Prematurity
77 M. Elizabeth Hartnett 7 Oxidative Damage in the Retina
93 Robert D. Stratton 8 The Role of Oxidative Stress in Hearing Loss
115 Colleen G. Le Prell and Josef M. Miller 9 Disorders of Children
133 Hirokazu Tsukahara and Masato Yashiro 10 Oxidative Stress in Oral Cavity: Interplay between Reactive Oxygen Species and Antioxidants in Health
Inflammation
and Cancer
155 Maurizio Battino
Maria Greabu and Bogdan Calenic 11 Oxidative Stress and the Skin
167 Christina L. Mitchell 12 Oxidative Stress in Osteoarticular Diseases
183 María José Alcaraz
Sergio Portal-Núñez
Juan A. Ardura and Pedro Esbrit 13 Gene Therapy to Reduce Joint Inflammation in Horses
193 Patrick Colahan
Rachael Watson
and Steve Ghivizzani 14 Muscle and Oxidative Stress
205 Reza Ghiasvand and Mitra Hariri 15 Role of Oxidants and Antioxidants in Male Reproduction
221 Ashok Agarwal
Hanna Tadros
Aaron Panicker and Eva Tvrdá 16 Role of Oxidants and Antioxidants in Female Reproduction
253 Ashok Agarwal
Hanna Tadros and Eva Tvrdá 17 Reactive Oxygen Species
Oxidative Stress
and Cardiovascular Diseases
281 Fatemeh Sharifpanah and Heinrich Sauer 18 Oxidative Stress and Antioxidant Imbalance: Respiratory Disorders
307 Surinder K. Jindal 19 Oxidative Stress and Type 1 Diabetes
319 Chao Liu
Clayton E. Mathews
and Jing Chen 20 Metabolic Syndrome
Inflammation
and Reactive Oxygen Species in Children and Adults
329 William E. Winter and Janet H. Silverstein 21 Oxidative Stress in Chronic Pancreatitis
339 Shweta Singh and Bechan Sharma 22 Wound Healing and Hyperbaric Oxygen Therapy Physiology: Oxidative Damage and Antioxidant Imbalance
347 James R. Wilcox and D. Scott Covington 23 Radiobiology and Radiotherapy
357 Justin Wray and Judith Lightsey 24 Chemotherapy-Mediated Pain and Peripheral Neuropathy: Impact of Oxidative Stress and Inflammation
367 Hassan A.N. El-Fawal
Robert Rembisz
Ryyan Alobaidi
and Shaker A. Mousa 25 Grape Polyphenol-rich Products with Antioxidant and Anti-inflammatory Properties
389 Eduarda Fernandes
Marisa Freitas
Renan C. Chisté
Elena Falqué
and Herminia Domínguez 26 Isotonic Oligomeric Proanthocyanidins
403 Hanbo Hu and Donald Armstrong 27 Superoxide Dismutase Mimics and Other Redox-active Therapeutics
415 Ines Batinic-Haberle and Artak Tovmasyan 28 Herbal Medicine: Past
Present
and Future with Emphasis on the Use of Some Common Species
471 Aneela Afzal and Mohammad Afzal 29 Ayurvedic Perspective on Oxidative Stress Management
483 Priyanka M. Jadhav 30 Clinical Trials and Antioxidant Outcomes
493 Carlos Palacio and Arshag D. Mooradian 31 Statistical Approaches to Make Decisions in Clinical Experiments
507 Albert Vexler and Xiwei Chen Index
561