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Focusing on food, herbals, and their chemical constituents, this book discusses how they contribute to health through control of metabolism, primarily as they relate to chronic disease development and treatment. Each chapter provides a comprehensive examination of the macronutrient, micronutrient, and phytochemical impact on drug action and includes advice on modification or supplementation in those cases where diet is a factor. The book describes the roles of genetic variation and polymorphism in determining nutrient/drug responses, how they might be "profiled" to identify those likely to demonstrate specific interactions, and who would benefit from adjuvant or complementary therapies.