This volume encompasses the Proceedings of the First International Colloquium on Physical and Chemical Information Transfer and Regulation of Reproduction and Ageing (Colloquium '74-PCITRRA), held at the F. Joliot Curie International House of Scientists, Varna, Bulgaria, October 7-14. This international event was made possible by the financial support afforded by the International Union of Biochemistry through Doctor P.N. Campbell, the International Union of Pure and Applied Biophysics through Doctor R.D. Keynes, UNESCO, and the Bulgarian Academy of Sciences. The characteristic and stimulating…mehr
This volume encompasses the Proceedings of the First International Colloquium on Physical and Chemical Information Transfer and Regulation of Reproduction and Ageing (Colloquium '74-PCITRRA), held at the F. Joliot Curie International House of Scientists, Varna, Bulgaria, October 7-14. This international event was made possible by the financial support afforded by the International Union of Biochemistry through Doctor P.N. Campbell, the International Union of Pure and Applied Biophysics through Doctor R.D. Keynes, UNESCO, and the Bulgarian Academy of Sciences. The characteristic and stimulating feature of the Colloquium'74-PCITRRA was the interdisciplinary audience (physicists, biologists, physicians, chemists, mathema ticians, engineers) and the orientation to information transfer and biological recognition in ageing. The at tention was focused on receptor transformation, espe cially that in ageing. Of special interest were the mathematical models and the theoretical basis of bio-information transfer, the age changes of the receptor recognition, the chemi cal information transfer in development, the hormone hormone interaction envisaged in their biophysical and biochemical aspects. The Colloquium '74 provided a very frank, critical and stimulating atmosphere for work and discussion on the latest results and concepts in topics of interest. The active role of the chairmen, Doctors. H.R. Arnstein, H.-J. Bartels, M. Blecher, J.A. Edwardson, M.R.P. Hall, E.V. Jensen, B.B. Saxena, J.R. Tata, and Ya.M. Varshavsky, was a great contribution in this respect and we would like to express our gratitude to them.
Mathematical Approach and Models of Regulatory Mechanisms.- A New Mathematical Approach of Hormonal Regulatory Mechanisms during Growth.- The Aliosteric Model of Monod, Wyman and Changeux and the Phenomenon of Rising B/F-Curves in Hormone-Antibody Reactions.- Oxytocin Effect of the Depolarized Rat Uterus: A Mathematical Approach Using System Identification.- Method for Measuring the Development of Control Systems in Time.- Analytical Investigation of the Oscillatory Phenomenon in Hormone Regulation.- Substrate Concentration and Its Effect on the Application of the Law of Mass Action-A Brownian Model.- Information Transfer in Ageing: An Allosteric Model of Hormonal Regulation.- Physical Mechanisms of Information Transfer.- The Conformational Changes of Biopolymers Retaining Their Initial Structure: A Necessary Stage of Intracellular Information Transfer.- Flexoelectric Model for Active Transport.- On the Role of the Conformation Changes at the Active Site for Allosteric Interactions.- A Possible Transfer of Physical Information through the Conversion of Mechanical Energy into Electrical: A Piezoelectric Effect in Proteins.- Protein Hormones and Their Receptor Interactions.- Effect of PGF-2alpha on the Synthesis of Placental Proteins and HPL.- Bioenergetic Effect of the Gonadotropic Hormones in Vivo.- Bioenergetic Effect of Thyreostimulating Hormone in Vitro.- Sex-Dependent Prolactin Pattern during Development.- The Correlation between the Binding of the Human Chorionic Gonadotropin to Luteal Cells and Plasma Membrane of Luteal Cells.- Particulate and Solubilized Hepatic Receptors for Glucagon, Insulin, Secretin, and Vasoactive Intestinal Polypeptide.- Protein Hormones Binding to Blood and Sperm Cells.- Small Molecules, Steroids, and Receptor Interactions.- Receptor Transformation - A Key Step in Estrogen Action.- Testicular Feminization Syndrome: A Model of Chemical Information Non-Transfer.- Effect of the Synthetic Estrogen Dioxydiphenylhexane on the Content of Nucleic Acids and Proteins during Development.- Possibility for a Direct Hormone-Hormone Interaction 2.- Cyclic AMP, Enzyme, and Hormone Networks in Bio-Development.- Growth and Developmental Hormones as Chemical Messengers.- Age-Dependent Sensitivity and Specific Isoenzyme Inhibition of Glucose-6-Phosphate Dehydrogenase by Dehydroepiandrosterone.- The Biosynthesis of Haemoglobin, Enzymes, and Nucleic Acids during Differentiation and Development of Erythroid Bone Marrow Cells.- Maturation Dependence of Adenylate Cyclase in Red Blood Cells.- Calcium and Cyclic AMP Effects of Rabbit Epididymal Spermatozoa.- Ontogenines as Carriers of Information during the Early Embryonic Development.- New Developments in Analytical Techniques and Apparatuses.- Spectrophotometric Equipment with Flash-Light Excitation.- A Rapid-Scanning Spectrophotometer.- Equipment for Data Registration and Processing in Fast Spectroscopy.- ECG Telemetrie Device and System for Population Attendance.- Modern Instrumentation in Protein Chemistry.- Physical and Chemical Transfer in Reproductive Processes.- Hypothalamic-Pituitary Function and Ageing.- Adenohypophysis and the Male Gonadal Axis Following Partial Body ?-Irradiation.- The Testicular Function Efficiency Determined by the Spermatogenic Activity Test (SAT) in Diabetic and Alcoholic Patients.- New Protein-Glycolipoprotein Complex Formation in Diluted Semen.- Changes in EEG and in the Activity of the Whole Cervical Vagus upon Application of Sex Hormones.- Epinephrine Reception by Sperm Cells.- Physical and Chemical Information Transfer in cAMP and Enzyme Network.- Control of Size and Shape in the Rodent Thymus.- The DNA Polymerase and the cAMP Content of Human Tonsillar Lymphocytes.- Insulin and Adrenalin Effect on Lung Triglyceride Lipases.- Magnetic Pumping of Blood in the Vascular System.- Biomagnetic Effect of the Constant Magnetic Field Action on Water and Physiological Activity.- List of Participants.
Mathematical Approach and Models of Regulatory Mechanisms.- A New Mathematical Approach of Hormonal Regulatory Mechanisms during Growth.- The Aliosteric Model of Monod, Wyman and Changeux and the Phenomenon of Rising B/F-Curves in Hormone-Antibody Reactions.- Oxytocin Effect of the Depolarized Rat Uterus: A Mathematical Approach Using System Identification.- Method for Measuring the Development of Control Systems in Time.- Analytical Investigation of the Oscillatory Phenomenon in Hormone Regulation.- Substrate Concentration and Its Effect on the Application of the Law of Mass Action-A Brownian Model.- Information Transfer in Ageing: An Allosteric Model of Hormonal Regulation.- Physical Mechanisms of Information Transfer.- The Conformational Changes of Biopolymers Retaining Their Initial Structure: A Necessary Stage of Intracellular Information Transfer.- Flexoelectric Model for Active Transport.- On the Role of the Conformation Changes at the Active Site for Allosteric Interactions.- A Possible Transfer of Physical Information through the Conversion of Mechanical Energy into Electrical: A Piezoelectric Effect in Proteins.- Protein Hormones and Their Receptor Interactions.- Effect of PGF-2alpha on the Synthesis of Placental Proteins and HPL.- Bioenergetic Effect of the Gonadotropic Hormones in Vivo.- Bioenergetic Effect of Thyreostimulating Hormone in Vitro.- Sex-Dependent Prolactin Pattern during Development.- The Correlation between the Binding of the Human Chorionic Gonadotropin to Luteal Cells and Plasma Membrane of Luteal Cells.- Particulate and Solubilized Hepatic Receptors for Glucagon, Insulin, Secretin, and Vasoactive Intestinal Polypeptide.- Protein Hormones Binding to Blood and Sperm Cells.- Small Molecules, Steroids, and Receptor Interactions.- Receptor Transformation - A Key Step in Estrogen Action.- Testicular Feminization Syndrome: A Model of Chemical Information Non-Transfer.- Effect of the Synthetic Estrogen Dioxydiphenylhexane on the Content of Nucleic Acids and Proteins during Development.- Possibility for a Direct Hormone-Hormone Interaction 2.- Cyclic AMP, Enzyme, and Hormone Networks in Bio-Development.- Growth and Developmental Hormones as Chemical Messengers.- Age-Dependent Sensitivity and Specific Isoenzyme Inhibition of Glucose-6-Phosphate Dehydrogenase by Dehydroepiandrosterone.- The Biosynthesis of Haemoglobin, Enzymes, and Nucleic Acids during Differentiation and Development of Erythroid Bone Marrow Cells.- Maturation Dependence of Adenylate Cyclase in Red Blood Cells.- Calcium and Cyclic AMP Effects of Rabbit Epididymal Spermatozoa.- Ontogenines as Carriers of Information during the Early Embryonic Development.- New Developments in Analytical Techniques and Apparatuses.- Spectrophotometric Equipment with Flash-Light Excitation.- A Rapid-Scanning Spectrophotometer.- Equipment for Data Registration and Processing in Fast Spectroscopy.- ECG Telemetrie Device and System for Population Attendance.- Modern Instrumentation in Protein Chemistry.- Physical and Chemical Transfer in Reproductive Processes.- Hypothalamic-Pituitary Function and Ageing.- Adenohypophysis and the Male Gonadal Axis Following Partial Body ?-Irradiation.- The Testicular Function Efficiency Determined by the Spermatogenic Activity Test (SAT) in Diabetic and Alcoholic Patients.- New Protein-Glycolipoprotein Complex Formation in Diluted Semen.- Changes in EEG and in the Activity of the Whole Cervical Vagus upon Application of Sex Hormones.- Epinephrine Reception by Sperm Cells.- Physical and Chemical Information Transfer in cAMP and Enzyme Network.- Control of Size and Shape in the Rodent Thymus.- The DNA Polymerase and the cAMP Content of Human Tonsillar Lymphocytes.- Insulin and Adrenalin Effect on Lung Triglyceride Lipases.- Magnetic Pumping of Blood in the Vascular System.- Biomagnetic Effect of the Constant Magnetic Field Action on Water and Physiological Activity.- List of Participants.
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