Edward K. Wagner

Basic Virology

By Edward K. Wagner, Martinez J. Hewlett, David C. Bloom et al.

• Broschiertes Buch

Produktbeschreibung

Ideal for the student seeking a solid understanding of the basic principles in this rapidly developing field, this best-selling text offers a comprehensive introduction to the fundamentals of virology. Featuring an enhanced art program now in full-color, the new edition has been updated throughout, including cutting-edge information on emerging viruses of medical importance and expanded coverage of viral pathogenesis, viral immunology, retroviruses and HIV/AIDS. New chapters have been added dealing with HIV and AIDS, viruses and cancer, generation and use of recombinant viruses and virus-like particles, viral evolution, network biology and viruses, and animal models and transgenics.The third edition is even more comprehensive and accessible, including chapter outlines, revised and expanded review questions, case studies, and cumulative end of section problems, which integrate topics covered in that section and challenge students to synthesize new material.

Produktdetails

• Verlag: Blackwell Publishers
• 3. Aufl.
• Seitenzahl: 582
• Erscheinungstermin: 5. Oktober 2007
• Englisch
• Abmessung: 280mm x 216mm x 31mm
• Gewicht: 1650g
• ISBN-13: 9781405147156
• ISBN-10: 1405147156
• Artikelnr.: 20897996

Autorenporträt

Edward K. Wagner (May 4, 1940 - January 21, 2006) was Professor of Molecular Biology and Biochemistry at the University of California Irvine. Martinez J. Hewlett is Professor Emeritus in the Department of Molecular and Cellular Biology at the University of Arizona. New to this edition, David C. Bloom is Associate Professor in the Department of Molecular Genetics and Microbiology at University of Florida and David Camerini is Assistant Professor in the Department of Molecular Biology and Biochemistry at the University of California Irvine.

Inhaltsangabe

Preface to the First Edition. Preface to the Second Edition. Preface to the
Third Edition. Acknowledgments. Part I: Virology and Viral Disease. 1.
Introduction - the Impact of Viruses on Our View of Life 2. 2. An Outline
of Virus Replication and Viral Pathogenesis. 3. Virus Disease in
Populations and Individual Animals. 4. Patterns of Some Viral Diseases of
Humans. Part II: Basic Properties of Viruses and Virus-Cell Interaction. 5.
Virus Structure and Classification. 6. The Beginning and End of the Virus
Replication Cycle. 7. Host Immune Response to Viral Infection - The Nature
of the Vertebrate Immune Response. 8. Strategies to Protect Against and
Combat Viral Infection. Part III: Working with Virus. 9. Visualization and
Enumeration of Virus Particles. 10. Replicating and Measuring Biological
Activity of Viruses. 11. Physical and Chemical Manipulation of the
Structural Components of Viruses. 12. Characterization of Viral Products
Expressed in the Infected Cell. 13. Viruses Use Cellular Processes to
Express Their Genetic Information. Part IV: Replication Patterns of
Specific Viruses. 14. Replication of Positive-sense RNA Viruses. 15.
Replication Strategies of RNA Viruses Requiring RNA-directed mRNA
Transcription as the First Step in Viral Gene Expression. 16. Replication
Strategies of Small and Medium-sized DNA Viruses. 17. Replication of Some
Nuclear-replicating Eukaryotic DNA Viruses with Large Genomes. 18.
Replication of Cytoplasmic DNA Viruses and "Large" Bacteriophages. 19.
Retroviruses: Converting RNA to DNA. 20. Human Immunodeficiency Virus Type
1 (HIV-1) and Related Lentiviruses. 21. Hepadnaviruses: Variations on the
Retrovirus Theme. PART V: Viruses: New Approaches and New Problems. 22. The
Molecular Genetics of Viruses. 23. Molecular Pathogenesis. 24. Viral
Bioinformatics and Beyond. 25. Viruses and the Future - Promises and
Problems. Appendix: Resource Center. Books of Historical and Basic Value.
Books on Virology. Molecular Biology and Biochemistry Texts. Detailed
Sources. Sources for Experimental Protocols. The Internet. Technical
Glossary. Index

Rezensionen

"This latest revision to the very successful Basic Virology is more than just a simple update... The new chapters are very timely and address current virology research topics including the important issues of molecular pathogenesis and bioinformatics. The text is well written and very understandable with excellent use of photos, diagrams, and tables to highlight and aid in the understanding of difficult issues. Instructors will find the text up to date and the figures readily adaptable to Powerpoint lectures. Students will be pleased to find the text engaging while presenting virology in a clear, concise, and enjoyable manner."
Professor Michael R. Roner, University of Texas, Arlington