M. A. Khamashta, St Thomas' Hospital, London, UK
Section 1: Clinical Aspects
1. Hughes Syndrome: History
M. A. Khamashta
2. Antiphospholipid Syndrome: An overview
David P. D Cruz
3. Epidemiology of Antiphospholipid Syndrome
Michelle Petri
4. Hemocytopenias in Antiphospholipid Syndrome
Carlomaurizio Montecucco and Roberto Caporali
5. Cardiac Manifestations in Antiphospholipid Syndrome
Josep Font and Ricard Cervera
6. Cerebral Ischemia in Antiphospholipid Syndrome
Debendra Pattanaik and Robin L. Brey
7. Cerebral Disease other than Stroke and tia in Antiphospholipid Syndrome
Giovanni Sanna
8. Skin Manifestations of Antiphospholipid Syndrome
Carlos A. Battagliotti
9. Kidney Disease in Antiphospholipid Syndrome
Mary-Carmen Amigo and Romeo García-Torres
10. Systemic Hypertension in Antiphospholipid Syndrome
Shirish R. Sangle and David P. D Cruz
11. Pulmonary Hypertension and Antiphospholipid Antibodies
Jean-Charles Piette and Beverley J. Hunt
12. Osteoarticular Manifestations of Antiphospholipid Syndrome
Maria G. Tektonidou and Haralampos M. Moutsopoulos
13. The Ear and Antiphospholipid Syndrome
Elias Toubi and Aharon Kessel
14. The Eye in Primary Antiphospholipid Syndrome
Cristina Castañon and Pedro A.Reyes
15. Primary Antiphospholipid Syndrome
Tonia L. Vincent and Charles G. Mackworth-Young
16. Catastrophic Antiphospholipid Syndrome
H. Michael Belmont
17. Obstetric Antiphospholipid Syndrome
T. Flint Porter, Robert M. Silver and D. Ware Branch
18. Infertility and Antiphospholipid Antibodies
Lisa R. Sammaritano
19. Transplantation of Solid Organs, Tissues and Prosthetic Devices in Patients with Antiphospholipid Antibodies
Dawn R. Wagenknecht and John A. McIntyre
20. Antiphospholipid Syndrome in Children
Lori B. Tucker and Rolando Cimaz
21. Ethnic and Geographic Variation in Antiphospholipid Syndrome
Wendell A. Wilson and Elena Cucurull
22. Antiphospholipid Syndrome: Differential Diagnosis
Beverley J. Hunt and Paul R. J. Ames
Section 2: Laboratory Investigation
23. Anticardiolipin Testing
Silvia S. Pierangeli
24. Lupus Anticoagulants: Mechanistic and Diagnostic Considerations
Jef M. M. C. Arnout and Jos Vermylen
25. ß2-glycoprotein I and Anti-ß2-glycoprotein I antibodies
Shinsuke Yasuda, Tatsuya Atsumi and Takao Koike
26. Antiprothrombin Antibodies
Maria Laura Bertolaccini
27. Antiphospholipid Syndrome in the Absence of Standard Antiphospholipid Antibodies: Associations with Other Autoantibodies
Robert A. S. Roubey
Section 3: Basic Aspects
28. Vascular Pathology of Antiphospholipid Antibody Syndrome
Gale A. McCarty
29. Placental Pathology in Antiphospholipid Syndrome
Ann L. Parke
30. Antiphospholipid Syndrome Experimental Models: Insight into the Etiology, Pathogenesis, and Treatments
Miri Blank, Ilan Krause and Yehuda Shoenfeld
31. Antiphospholipid Antibody-Induced Pregnancy Loss and Thrombosis
Guillermina Girardi and Jane E. Salmon
32. Mechanism of Thrombosis in Antiphospholipid Syndrome: Binding to Platelets
Joan-Carles Reverter and Dolors Tàssies
33. Interaction of Antiphospholipid Antibodies with Endothelial Cells
Pier Luigi Meroni, Elena Raschi, Cinzia Testoni, Arianna Parisio, Maria Gerosa and Maria Orietta Borghi
34. The Influence of Antiphospholipid Antibodies on the Protein C Pathway
Philip G. de Groot and Ronald H. W. M. Derksen
35. Contribution of Tissue Factor to the Pathogenesis of Thrombosis in Patients with Antiphospholipid Syndrome
Chary López-Pedrera, Francisco Velasco and Maria J. Cuadrado
36. Annexins in Antiphospholipid Syndrome
Jacob H. Rand and Xiao-Xuan Wu
37. Plasminogen Activation, Fibrinolysis and Cell Proteolytic Activity in Antiphospholipid Syndrome
Eduardo Anglés Cano
38. Lessons from Sequence Analysis of Monoclonal Antiphospholipid Antibodies
Ian P. Giles, David A. Isenberg and Anisur Rahman
39. Apoptosis and Antiphospholipid Antibodies
Kieth B. Elkon, Neelufar Mozaffarian and Natalia Tishkevich
40. Accelerated Atherogenesis and Antiphospholipid Anti
