Herman Friedman / Steven Specter / Mauro Bendinelli (eds.)

In vivo Models of HIV Disease and Control

Ed. by H. Friedman, S. Specter and M. Bendinelli

• Gebundenes Buch

Produktbeschreibung

An AIDS vaccine is still elusive and HIV treatment continues to develop multidrug resistance at alarming rates. Because of the similarities between HIV and immune deficiency infections in a variety of animals, it is only natural that scientists use these animals as models to study pathogenesis, treatment, vaccine development and many other aspects of HIV.

Part of the series Infectious Agents and Pathogenesis, this volume reviews the immune deficiency virus in a variety of hosts. Pathogenesis, vaccine and drug development, epidemiology, and the natural history of the monkey, mouse, cat, cow, horse, and other animal viruses are detailed and compared to HIV. Also included are chapters on the history and future of animal models, as well as a chapter on ethical and safety considerations in using animal models for AIDS studies.

Produktdetails

• Infectious Agents and Pathogenesis
• Verlag: Springer, Berlin
• 2006
• Seitenzahl: 456
• Erscheinungstermin: 21. Dezember 2005
• Englisch
• Abmessung: 241mm x 160mm x 33mm
• Gewicht: 1122g
• ISBN-13: 9780387257402
• ISBN-10: 0387257403
• Artikelnr.: 15202641

Autorenporträt

Herman Friedman, University of South Florida, Tampa, FL, USA / Steven Specter, University of South Florida, Tampa, FL, USA / Mauro Bendinelli, University of Pisa, Pisa, Italy

Inhaltsangabe

Preface to the Series.
- Introduction.
- Historical Perspective.
- Animal Model Systems of AIDS and HIV-Associated Disease.
- Chemokines and their Receptors and the Neuropathogenesis of HIV-1 Infection.
- SCID Mice Transplanted with Human Cells as Small Animal Models in AIDS Research.
- SIV as a Model for AIDS Pathogenesis Studies.
- SIV Infection of Macaques as a Model for AIDS Drug Studies.
- FIV as a Model for HIV: an Overview.
- FIV as a Model for AIDS Pathogenesis Studies: In Vivo Models of HIV Disease and Control.
- Drugsof Abuse, AIDS, and the FIV Model.
- FIV as a Model for AIDS Vaccine Studies.
- FIV as a Model for HIV Treatment.
- Equine Infectious Anemia Virus as a Model for Lentiviral Pathogenesis.
- Studies of the Structure of Caprine Arthritis-Encephalitis Virus Surface Envelope Glycoprotein.
- Future Perspectives.
- Index.