Design and Analysis of Biomolecular Circuits (eBook, PDF)

Engineering Approaches to Systems and Synthetic Biology
Redaktion: Koeppl, Heinz; Di Bernardo, Mario; Setti, Gianluca; Densmore, Douglas

• Format: PDF

Produktbeschreibung

This book is devoted to the design and analysis of biomolecular circuits as considered in systems biology and synthetic biology. The aim of the book is to present in a coherent framework some of the most recent work on the analysis, simulation and design of biomolecular circuits and systems, reflecting the interdisciplinary and collaborative nature of the field. The results discussed range from how these systems should be modeled and analyzed, to how they should be physically designed and implemented. Drawing parallels to electronic circuit design, this book's contents are organized to reflect what the editors believe are the important, necessary steps to build complex synthetic circuits. Coverage includes analysis and simulation, modularity and abstraction, design and standardization, and enabling technologies. Each of these themes is organized in different chapters that are self-contained so that they can be read individually by experts but also read sequentially by someone wanting to get an overview of the field. This book is intended for computational scientists, e.g. mathematicians, physicists, computer scientist or engineers as well as for researchers from the life sciences. Every effort has been made to make the presentation accessible to a broad, multi-disciplinary audience.

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Produktdetails

• Verlag: Springer-Verlag GmbH
• Seitenzahl: 402
• Englisch
• ISBN-13: 9781441967664
• Artikelnr.: 38307024

Inhaltsangabe

Simulation and Analysis of Bio-Molecular Circuits.- Introduction to Chemical Kinetics.- Computer Science Models to Describe Bio-Molecular Circuits.- Limitation of Current Modeling Approaches.-Abstraction in System Design; Abstraction Hierarchies and their use in CAD of Electronic Circuits.- Current efforts in standardization of Biological Parts.- Case Studies.-Biological Modules.- Enabling Technologies for Synthetic and Systems Biology.

Rezensionen

From the reviews:

"This collection of papers is an excellent reference for anyone who would like to learn more about the engineering and computing side of systems and synthetic biology. ... this clear and detailed volume will help to introduce mathematicians, engineers, and computer scientists to an application of their fields in biology. It will also serve biologists who want to know more about how in silico technologies can be an important part of the arsenal used to understand and create biological systems." (Sara Kalvala, ACM Computing Reviews, June, 2012)