Biomedical Sciences

Essential Laboratory Medicine
Herausgegeben von Iles, Ray; Docherty, Suzanne

• Gebundenes Buch

Produktbeschreibung

Biomedical Sciences is an indispensable, all encompassing core textbook for first/ second year biomedical science students that will support them throughout their undergraduate career. The book includes the key components of the IBMS accredited degree programmes, plus sections on actual practice in UK hospital laboratories (including the compilation of a reflective portfolio).

The book is visually exciting, and written in an interesting and accessible manner while maintaining scientific rigour. Highlighted boxes within the text link the theory to actual clinical laboratory practice for example, the histopathology chapter includes a photographically illustrated flow chart of the progress of a specimen through the histopathology lab, so that students can actually see how the specimen reception/inking/cut-up/cassette/block/section/stain system works, with an emphasis on the safety procedures that ensure specimens are not confused).

Produktdetails

• Verlag: Wiley & Sons
• Artikelnr. des Verlages: 14599775000
• 1. Auflage
• Seitenzahl: 438
• Erscheinungstermin: 30. Januar 2012
• Englisch
• Abmessung: 260mm x 197mm x 28mm
• Gewicht: 1218g
• ISBN-13: 9780470997758
• ISBN-10: 0470997753
• Artikelnr.: 33368093

Autorenporträt

Professor Ray Iles and Dr Suzanne Docherty, School of Health & Social Sciences, Middlesex University, Hendon Campus, London, UK. Ray Iles has experience of writing a chapter of Kumar & Clark's Clinical Medicine (one of the market leading textbooks for medical students) and would like to provide the same kind of core textbook for biomedical science students.

Inhaltsangabe

List of Contributors xi Preface xiii Chapter 1 Anatomy and physiology of
major organ systems 1 Ray K. Iles, Iona Collins and Suzanne M. Docherty 1.1
The skeletal system 1 1.2 The digestive system 6 1.3 The cardiovascular
system 11 1.4 The urinary system 17 1.5 Respiratory system 21 1.6 The
nervous system 23 1.7 The endocrine system 31 Bibliography 33 Chapter 2
Pathophysiology 35 Suzanne M. Docherty 2.1 Pathophysiology: a definition 35
2.2 Introduction to epidemiology 35 2.3 Introduction to pharmacology 38 2.4
Gastroenterology 44 2.5 Liver, biliary tract and pancreatic disease 50 2.6
Rheumatology 56 2.7 Urinary tract disease 59 2.8 Cardiovascular disease 65
2.9 Respiratory disease 76 2.10 Endocrine disease 80 Bibliography 88
Chapter 3 Clinical cell biology and genetics 89 Ray K. Iles and Stephen A.
Butler 3.1 The cell 89 3.2 Genetics 103 3.3 Human genetic disorders 116 3.4
Important techniques in molecular cell biology 136 Bibliography 138 Chapter
4 Cellular pathology 139 Christopher M. Stonard and Jennifer H. Stonard
Part I: Principles of cellular pathology 139 4.1 Structure and function of
normal cells, tissues and organs 139 4.2 Tissues and organs 140 4.3
Cellular responses to injury 141 4.4 Tissue responses to injury: acute
inflammation 143 4.5 Tissue responses to injury: chronic inflammation 149
4.6 Healing and repair 151 4.7 Hyperplasia and hypertrophy 154 4.8
Atherosclerosis 155 4.9 Thrombosis and embolism 157 4.10 Ischaemia and
infarction 159 4.11 Amyloid and amyloidosis 160 4.12 Infections of
histological importance 162 4.13 Metaplasia, dysplasia and carcinoma in
situ 165 4.14 Neoplasia 168 Part II: Clinical application and laboratory
techniques 175 4.15 Sampling modalities 175 4.16 Fixation 178 4.17 Specimen
dissection 180 4.18 Processing and embedding 182 4.19 Microtomy 184 4.20
Standard staining methods and procedures 186 4.21 Frozen section 190 4.22
Immunohistochemistry 191 4.23 Cytopathology 196 4.24 Electron microscopy
197 4.25 In situ hybridization 201 Bibliography 203 Chapter 5 Clinical
chemistry 205 Ray K. Iles and Stephen A. Butler Introduction 205 Part I:
Analytical methods 205 5.1 Sample collection 205 5.2 Analytical methods in
clinical chemistry laboratories 210 5.3 Summary: common clinical tests for
sample analytes 231 Part II: Clinical assessments 232 5.4 Urea and
electrolytes (U and Es) 232 5.5 Metabolism and gastrointestinal markers 234
5.6 Renal function tests 236 5.7 Liver function tests 237 5.8 Heart disease
and lipid disorder tests 238 5.9 Pancreatic function tests 240 5.10 Bone
disease assessment 241 5.11 Endocrinological assessments 241 5.12 Pregnancy
tests and pregnancy clinical chemistry 249 5.13 Therapeutic drug monitoring
and toxicology 251 5.14 Clinical chemistry at the extremes of age 253 5.15
Cancer biomarkers 254 Bibliography 259 Chapter 6 Medical microbiology 261
Sarah J. Furrows and Catherine S. Fontinelle Introduction 261 6.1 Overview
of microorganisms 261 6.2 Laboratory investigation of infection 265 6.3
Bacteria 277 6.4 Fungi 284 6.5 Parasitology --- protozoa and helminths 288
6.6 Viruses 290 6.7 Prions 297 6.8 Infections in the immunocompromised
patient 298 6.9 Healthcare associated infections 299 6.10 Antimicrobial
agents 302 6.11 Vaccines 307 6.12 Conclusion 309 Bibliography 309 Chapter 7
Clinical immunology 311 Ray K. Iles and Ivan M. Roitt Part I: The
fundamentals of immunology 311 7.1 Overview of the immune system 311 7.2
Overview of the immune response 316 7.3 MHC genotyping, autoimmunity and
susceptibility to disease 321 7.4 Physical age and immunocompetency 322
Part II: Laboratory investigations and immune assessments 323 7.5
Inflammation and chronic infection 323 7.6 Autoimmune diseases 324 7.7
Transplant rejection 325 7.8 Hypersensitivities 326 7.9 Immune deficiency
326 Bibliography 328 Chapter 8 Haematology and transfusion science 329
Suzanne M. Docherty 8.1 Introduction and components of blood 329 8.2
Routine laboratory blood tests 332 8.3 Haemopoiesis 336 8.4 Red blood cell
structure, disorders and metabolism 337 8.5 Haemoglobin 342 8.6 Anaemia 353
8.7 Benign white blood cell disorders 359 8.8 Haemostasis 361 8.9
Coagulation disorders 366 8.10 Myeloproliferative disorders 371 8.11
Haematological malignancies 373 8.12 Complement 378 8.13 Blood transfusion
380 8.14 Blood products 390 8.15 Haemopoetic stem cell transplantation 393
Bibliography 395 Chapter 9 Professional practice and biomedical science 397
David Ricketts 9.1 What is a biomedical scientist? 397 9.2 The IBMS 397 9.3
Professional practice and the role of the HPC 398 9.4 Standards of
proficiency --- biomedical scientists 399 9.5 Expectations of a health
professional 400 9.6 Professional relationships 401 9.7 The skills required
for the application of practice 401 9.8 Knowledge, understanding and skills
402 9.9 Standards of conduct, performance and ethics 403 9.10 CPD 403 9.11
Critical reflection 404 9.12 IBMS CPD scheme 404 9.13 The professional
biomedical scientist as an agent for change in the wider healthcare setting
405 Appendix 407 Index 413