Gareth Thomas

Medicinal Chemistry (eBook, PDF)

An Introduction

• Format: PDF

Produktbeschreibung

Medicinal Chemistry: An Introduction, Second Edition provides a comprehensive, balanced introduction to this evolving and multidisciplinary area of research. Building on the success of the First Edition, this edition has been completely revised and updated to include the latest developments in the field. Written in an accessible style, Medicinal Chemistry: An Introduction, Second Edition carefully explains fundamental principles, assuming little in the way of prior knowledge. The book focuses on the chemical principles used for drug discovery and design covering physiology and biology where relevant. It opens with a broad overview of the subject with subsequent chapters examining topics in greater depth. From the reviews of the First Edition: "It contains a wealth of information in a compact form" ANGEWANDTE CHEMIE, INTERNATIONAL EDITION "Medicinal Chemistry is certainly a text I would chose to teach from for undergraduates. It fills a unique niche in the market place." PHYSICAL SCIENCES AND EDUCATIONAL REVIEWS

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Produktdetails

• Verlag: John Wiley & Sons
• Seitenzahl: 646
• Erscheinungstermin: 13. Oktober 2008
• Englisch
• ISBN-13: 9780470518304
• Artikelnr.: 37294199

Autorenporträt

Dr Gareth Thomas, The University of Portsmouth, UK.

Inhaltsangabe

Preface Acknowledgements. Abbreviations. Chapter 1. An Introduction to
Drugs, their Action and Discovery. Chapter 2. Drug Structure and
Solubility. Chapter 3. Structure-activity and quantitative structures
relationships. Chapter 4. Computer aided drug design. Chapter 5.
Combinatorial Chemistry. Chapter 6. Drugs from natural sources. Chapter 7.
Biological Membranes. Chapter 8. Receptors and Messengers. Chapter 9.
Enzymes. Chapter 10. Nucleic Acids. Chapter 11. Pharmacokinetics. Chapter
12. Drug metabolism. Chapter 13. Complexes and chelating agents. Chapter
14. Nitric oxide. Chapter 15. An Introduction to drug and analogue
synthesis. Chapter 16. Drug Development and Production. Selective further
reading. Answers to Questions. Index.

Rezensionen

"The many strengths of this introductory text include its seamless integration of biochemistry and pharmacology to direct drug discovery." ( Journal of Medicinal Chemistry , September 2008)