Herbal Drug for the Management of Infectious Diseases The book is a comprehensive compilation of herbal drug applications for the treatment and management of infectious diseases and addresses issues related to development, challenges, and future prospects associated with the use of herbal medicine. The use of herbal medicines has evolved in various cultures around the world over many millennia. In many developing Asian and African countries, the use of herbal medicines, as supplied by traditional medicinal practitioners, has always been popular. In the last two to three decades, many…mehr
Herbal Drug for the Management of Infectious Diseases
The book is a comprehensive compilation of herbal drug applications for the treatment and management of infectious diseases and addresses issues related to development, challenges, and future prospects associated with the use of herbal medicine.
The use of herbal medicines has evolved in various cultures around the world over many millennia. In many developing Asian and African countries, the use of herbal medicines, as supplied by traditional medicinal practitioners, has always been popular. In the last two to three decades, many people in developed countries have begun to turn to alternative or complementary therapies, including the use of herbal medicines, nutraceuticals, functional foods, and other supplements. This resurgence in interest in plant-derived medicines is partly due to the growing dissatisfaction with allopathic medicines, as well as the perception that plant-derived medicines are natural and therefore pure and without side effects, and the progress in the production of higher quality herbal medicines including some with proven clinical efficacy and safety.
Infectious diseases are generally caused by pathogenic microorganisms, like bacteria, viruses, parasites, or fungi, and are a significant cause of morbidity and mortality worldwide. Therefore, the 16 chapters of this book have been intentionally sequenced to cover the therapeutic potential and applications of herbal extracts and phytochemicals for the management of various infectious diseases. Disease pathophysiology, an overview of current medication or treatment, in-vitro and in-vivo evaluations of relevant biological activities of herbal extracts and phytochemicals, mechanisms of action, clinical trials, and novel technologies for the delivery of herbal bioactive compounds as well as patents have also been included.
Audience Chemists, pharmaceutical scientists, biologists, herbal/Ayurvedic/medicinal practitioners, as well all those in the medical sciences working on medicinal plants and infectious diseases.
Inderbir Singh, PhD, is a professor at Chitkara College of Pharmacy, Chitkara University, Patiala, Punjab, and has a total experience of 19 years in both industry and academia. He has published more than 103 research/review articles in national and international journals, 6 books, 15 book chapters, 2 patents granted, and 11 patents (applied). Rakesh K. Sindhu, PhD, is an associate professor in the Department of Pharmacognosy and Natural Products, Chitkara College of Pharmacy, Chitkara University, Rajpura, Punjab, India. He has published more than 50 research papers in reputed journals, three books, and 6 patents. Atul A. Shirkhedkar, PhD, is a professor and vice-principal of the Dept. of Pharm. Chem., R. C. Patel Institute of Pharmaceutical Education and Research, Shirpur, India. He has published more than 160 research papers in National and International journals. Pharkphoom Panichayupakaranant is at the Department of Pharmacognosy and Pharmaceutical Botany, Prince of Songkla University, Thailand. He has published more than 200 publications in ISI journals, 12 patents, and received 7 international invention awards.
Inhaltsangabe
Preface xvii
1 Essential Oils as Potent Antimicrobial Agents 1 Rakesh K. Sindhu, Prabhjot Kaur, Parneet Kaur, Sumitra Singh and Simona Cavalu
1.1 Introduction 2
1.2 Essential Oils 3
1.3 Chemical Composition of Essential Oils 5
1.4 Mechanism of Action of Essential Oils as? Antimicrobials 11
1.5 Factors Affecting Antimicrobial Activity of Essential Oil 13
1.6 Essential Oils as Combination Therapy 13
1.7 Evaluation of Antimicrobial Efficacy of Essential Oils 14
1.8 Conclusion and Future Perspectives 16
2 Herbal Antibiotics for Treating Drug-Resistant Bacteria 23 Haixia Chen and Shuqin Li
2.1 Introduction 24
2.2 Resistance Mechanism of Strains 25
2.3 The Classification of Herbal Secondary Metabolites for Drug Resistance 28
2.4 Mechanism 41
2.5 Conclusion and Perspectives 44
3 Phytopharmaceuticals for the Management of Fungal Infections 55 Kampanart Huanbutta and Tanikan Sangnim
3.1 Introduction 55
3.2 Nature of Fungi and Classification of Fungal Disease 56
3.3 Epidemiology of Fungal Infection 58
3.4 Limitations of Modern Medicines 60
3.5 Medicinal Plants With Antifungal Activities 61
3.6 Phytopharmaceuticals With Antifungal Activities 63
3.7 Activity and Mechanism of Action of Antifungal Drugs and Phytopharmaceuticals 68
3.8 Conclusion and Future Prospect of? Phytopharmaceuticals for the Management of? Fungal Infections 72
4 Herbal Bioactives for the Management of Influenza Viral Infection 85 Shaveta Bhardwaj, Jobanpreet Kaur, Atinderpal Kaur, Satvinder Kaur, Anu Jindal and Inderbir Singh
4.1 Introduction 86
4.2 Various Herbal Bioactives With Anti-Influenza Property 87
4.3 Mechanism of an Anti-Influenza Effect 91
4.4 Conclusion 93
5 Herbal Bioactives for Treating Respiratory Infections 101 Chandrakantsing V. Pardeshi, Sagar R. Pardeshi, Jitendra B. Naik, Atul A. Shirkhedkar and Sanjay J. Surana
5.1 Introduction 101
5.2 Overview of Respiratory Tract Infections 103
5.3 Herbal Bioactives for the Management of RTIs 108
5.4 Bioactives and Their Derivatives Against Novel Coronavirus Disease 112
5.5 Emerging Drug Delivery Strategies for Biomedicines in the Management of RTIs 113
5.6 Clinical Status: Opportunities and Challenges 120
5.7 Patent Perspectives 120
5.8 Future Perspectives 122
5.9 Conclusion 122
6 Herbal Bioactives for the Treatment of Gastrointestinal Tract Disorders 133 Manish Kumar, Inderjeet Verma, Rakesh Kumar Sindhu and Rishabh Srivastava
6.1 Introduction 134
6.2 Classification of GIT Disorders 134
6.3 The Science of Herbal Medicine 135
6.4 Need of Herbal Medicine 143
6.5 Indirect Adverse Effects of Herbal Therapy 144
6.6 Herbal Bioactive-Based Formulation 144
6.7 Recent Patents for Herbal Drug Delivery Systems 148
6.8 Future Perspective 148
6.9 Conclusion 148
7 Herbal Drugs for the Treatment of Ocular Infections 157 A. A. Shirkhedkar, Mukesh S. Patil, A. S. Patil and Inderbir Singh
7.1 Introduction 158
7.2 Eye Essential Anatomy and Physiology 159
7.3 Preparation and Method of Use 161
7.4 Modern Investigations and Findings 163
7.5 Patents Recently Issued on Herbal Formulations 170
1 Essential Oils as Potent Antimicrobial Agents 1 Rakesh K. Sindhu, Prabhjot Kaur, Parneet Kaur, Sumitra Singh and Simona Cavalu
1.1 Introduction 2
1.2 Essential Oils 3
1.3 Chemical Composition of Essential Oils 5
1.4 Mechanism of Action of Essential Oils as? Antimicrobials 11
1.5 Factors Affecting Antimicrobial Activity of Essential Oil 13
1.6 Essential Oils as Combination Therapy 13
1.7 Evaluation of Antimicrobial Efficacy of Essential Oils 14
1.8 Conclusion and Future Perspectives 16
2 Herbal Antibiotics for Treating Drug-Resistant Bacteria 23 Haixia Chen and Shuqin Li
2.1 Introduction 24
2.2 Resistance Mechanism of Strains 25
2.3 The Classification of Herbal Secondary Metabolites for Drug Resistance 28
2.4 Mechanism 41
2.5 Conclusion and Perspectives 44
3 Phytopharmaceuticals for the Management of Fungal Infections 55 Kampanart Huanbutta and Tanikan Sangnim
3.1 Introduction 55
3.2 Nature of Fungi and Classification of Fungal Disease 56
3.3 Epidemiology of Fungal Infection 58
3.4 Limitations of Modern Medicines 60
3.5 Medicinal Plants With Antifungal Activities 61
3.6 Phytopharmaceuticals With Antifungal Activities 63
3.7 Activity and Mechanism of Action of Antifungal Drugs and Phytopharmaceuticals 68
3.8 Conclusion and Future Prospect of? Phytopharmaceuticals for the Management of? Fungal Infections 72
4 Herbal Bioactives for the Management of Influenza Viral Infection 85 Shaveta Bhardwaj, Jobanpreet Kaur, Atinderpal Kaur, Satvinder Kaur, Anu Jindal and Inderbir Singh
4.1 Introduction 86
4.2 Various Herbal Bioactives With Anti-Influenza Property 87
4.3 Mechanism of an Anti-Influenza Effect 91
4.4 Conclusion 93
5 Herbal Bioactives for Treating Respiratory Infections 101 Chandrakantsing V. Pardeshi, Sagar R. Pardeshi, Jitendra B. Naik, Atul A. Shirkhedkar and Sanjay J. Surana
5.1 Introduction 101
5.2 Overview of Respiratory Tract Infections 103
5.3 Herbal Bioactives for the Management of RTIs 108
5.4 Bioactives and Their Derivatives Against Novel Coronavirus Disease 112
5.5 Emerging Drug Delivery Strategies for Biomedicines in the Management of RTIs 113
5.6 Clinical Status: Opportunities and Challenges 120
5.7 Patent Perspectives 120
5.8 Future Perspectives 122
5.9 Conclusion 122
6 Herbal Bioactives for the Treatment of Gastrointestinal Tract Disorders 133 Manish Kumar, Inderjeet Verma, Rakesh Kumar Sindhu and Rishabh Srivastava
6.1 Introduction 134
6.2 Classification of GIT Disorders 134
6.3 The Science of Herbal Medicine 135
6.4 Need of Herbal Medicine 143
6.5 Indirect Adverse Effects of Herbal Therapy 144
6.6 Herbal Bioactive-Based Formulation 144
6.7 Recent Patents for Herbal Drug Delivery Systems 148
6.8 Future Perspective 148
6.9 Conclusion 148
7 Herbal Drugs for the Treatment of Ocular Infections 157 A. A. Shirkhedkar, Mukesh S. Patil, A. S. Patil and Inderbir Singh
7.1 Introduction 158
7.2 Eye Essential Anatomy and Physiology 159
7.3 Preparation and Method of Use 161
7.4 Modern Investigations and Findings 163
7.5 Patents Recently Issued on Herbal Formulations 170
