Leading interventional cardiologists, including Patrick Serruys, Eric Topol, David Holmes, Thomas Luscher and others provide the gold-standard reference on the treatment of restenosis (coronary artery blockage) for interventional cardiologists. Dr. Serruys, who pioneered the use of drug-eluting stents, and other pioneers in the field cover everything from non-invasive imaging, to eluting stents, to brachytherapy through to the latest molecular biology-based treatments including antisense, stem cells and gene therapy, making this an essential reference for all interventional cardiologists.
Leading interventional cardiologists, including Patrick Serruys, Eric Topol, David Holmes, Thomas Luscher and others provide the gold-standard reference on the treatment of restenosis (coronary artery blockage) for interventional cardiologists. Dr. Serruys, who pioneered the use of drug-eluting stents, and other pioneers in the field cover everything from non-invasive imaging, to eluting stents, to brachytherapy through to the latest molecular biology-based treatments including antisense, stem cells and gene therapy, making this an essential reference for all interventional cardiologists.
Artikelnr. des Verlages: 11992714, 978-1-58829-491-3
2007
Seitenzahl: 492
Erscheinungstermin: 27. August 2007
Englisch
Abmessung: 260mm x 183mm x 35mm
Gewicht: 1226g
ISBN-13: 9781588294913
ISBN-10: 1588294919
Artikelnr.: 22702846
Autorenporträt
Henricus J. Duckers, University of Rotterdam, The Netherlands / Patrick W. Serruys, University of Rotterdam, The Netherlands / Elizabeth G. Nabel, National Institutes of Health, Bethesda, MD, USA
Inhaltsangabe
Pathophysiology and Diagnosis.- Unraveling the Complex Process of Restenosis From Bench to Bedside.- Epidemiology and Pathogenesis of Restenosis.- Clinical Presentation of Restenosis.- Pathological Anatomy of Restenosis.- The Influence of Shear Stress on Restenosis.- The Immune System in the Pathogenesis of Vascular Proliferative Disease.- Animal Restenosis Models.- Genetic Basis of Restenosis.- The Genomics of Restenosis.- Gene-Expression Profiling and Restenosis.- Proteomics and Restenosis.- Contribution of Circulating Progenitor Cells to Vascular Repair and Lesion Formation.- Cell Cycle Regulators and Vascular Proliferative Diseases.- Arterial Remodeling.- The Role of eNOS in Vascular Diseases.- Diagnosis of Restenosis.- The Use of Pressure Gradient in the Diagnosis of Restenosis.- The Use of Radio Isotopes in the Diagnosis of Vascular Proliferative Disease.- Magnetic Resonance Imaging for Restenosis.- Coronary Imaging With Multislice Spiral Computed Tomography.- Therapy of Restenosis.- Pharmacotherapy of Restenosis.- Brachytherapy.- Preclinical Data of Eluting Stents.- Clinical Data of Eluting Stents.- Biodegradable Stents.- Biotechnology in the Treatment of Restenosis.- Vascular Gene Therapy.- Antisense and ODN Transcription Factors in the Treatment of Vascular Proliferative Disease.- Cell Cycle Approaches to the Treatment of In-Stent Restenosis.- Local Gene and Cell Delivery Devices.
Pathophysiology and Diagnosis.- Unraveling the Complex Process of Restenosis From Bench to Bedside.- Epidemiology and Pathogenesis of Restenosis.- Clinical Presentation of Restenosis.- Pathological Anatomy of Restenosis.- The Influence of Shear Stress on Restenosis.- The Immune System in the Pathogenesis of Vascular Proliferative Disease.- Animal Restenosis Models.- Genetic Basis of Restenosis.- The Genomics of Restenosis.- Gene-Expression Profiling and Restenosis.- Proteomics and Restenosis.- Contribution of Circulating Progenitor Cells to Vascular Repair and Lesion Formation.- Cell Cycle Regulators and Vascular Proliferative Diseases.- Arterial Remodeling.- The Role of eNOS in Vascular Diseases.- Diagnosis of Restenosis.- The Use of Pressure Gradient in the Diagnosis of Restenosis.- The Use of Radio Isotopes in the Diagnosis of Vascular Proliferative Disease.- Magnetic Resonance Imaging for Restenosis.- Coronary Imaging With Multislice Spiral Computed Tomography.- Therapy of Restenosis.- Pharmacotherapy of Restenosis.- Brachytherapy.- Preclinical Data of Eluting Stents.- Clinical Data of Eluting Stents.- Biodegradable Stents.- Biotechnology in the Treatment of Restenosis.- Vascular Gene Therapy.- Antisense and ODN Transcription Factors in the Treatment of Vascular Proliferative Disease.- Cell Cycle Approaches to the Treatment of In-Stent Restenosis.- Local Gene and Cell Delivery Devices.
Rezensionen
From the reviews:
"This is a comprehensive review of the problem of restenosis, from the basic science to clinical management. ... The audience includes interventional cardiology fellows and interventional cardiologists. The book describes the difficulties that cardiologists face trying to prevent and manage restenosis. ... Each chapter includes extensive references. This is a complete, state-of-the-art review of restenosis, covering all aspects of restenosis from pathophysiology to therapeutic management. The authors are leaders in interventional cardiology with extensive clinical experience in the field." (Adriana Maria Rosario, Doody's Review Service, December, 2007)
"A multiauthored, comprehensive compendium of virtually all aspects of the restenotic process after balloon- or stent-induced arterial injury. ... The text is written by a blueribbon panel of authors who provide an in-depth coverage of the topics. Many of the clinical chapters offer anexcellent historical perspective on the problem of restenotis. ... Recommended Readership: Interventional (clinical and research) cardiologists and interventional fellows." (John F. Bresnahan, Mayo Clinic Proceedings, Vol. 83 (4), April, 2008)
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