Kamel Khalili, Kuan-Teh Jeang

Viral Oncology (eBook, PDF)

Basic Science and Clinical Applications

• Format: PDF

Produktbeschreibung

Clinical oncologists and researchers now have a comprehensive single source of current information on cancer viruses obtained from bench and bedside. This important refernce allows further development of translational approaches for the effective treatment of patients with virus-associated malignancies. The book contains 25 chapters covering basic and clinical aspects of viruses, including HPV, HBV, HCV, polyomaviruses, Kaposi's associated viruses, retroviruses (including HIV-1 associated malignancies), and EBV. Several chapters are devoted to basic science of oncogenic viruses for the study of their pathogenesis, drug development, and employment of viral vectors for vaccine and gene therapy. Clinical materials are embedded within chapters, and there are also complementary, clinically based chapters describing natural courses and treatments.

---

Dieser Download kann aus rechtlichen Gründen nur mit Rechnungsadresse in A, B, BG, CY, CZ, D, DK, EW, E, FIN, F, GR, HR, H, IRL, I, LT, L, LR, M, NL, PL, P, R, S, SLO, SK ausgeliefert werden.

Produktdetails

• Verlag: John Wiley & Sons
• Seitenzahl: 496
• Erscheinungstermin: 10. August 2010
• Englisch
• ISBN-13: 9780470930564
• Artikelnr.: 37300988

Autorenporträt

Kamel Khalili, PhD, Professor and Chair, Department of Neuroscience, Temple University, and Kuan-Teh Jeang, MD, PhD, Head, Molecular Virology Section, National Institute of Allergy and Infectious Diseases, NIH, are among the leading scientists in the field of human DNA and RNA viruses. Each of them has more than 25 years' experience in studying oncogenic viruses.

Inhaltsangabe

Foreword. Preface. Contributors. 1 HUMAN PAPILLOMAVIRUS-ASSOCIATED CANCERS
(Rachel A. Katzenellenbogen and Denise A. Galloway). 2 MOLECULAR EVENTS
ASSOCIATED WITH HUMAN PAPILLOMAVIRUS-INDUCED HUMAN CANCERS (Amy Baldwin and
Karl Münger). 3 THE ROLE OF THE HUMAN PAPILLOMAVIRUS E6 ONCOPROTEIN IN
MALIGNANT PROGRESSION (Miranda Thomas, David Pim, and Lawrence Banks). 4 JC
VIRUS ASSOCIATION WITH BRAIN TUMORS: THE ROLE OF T ANTIGEN AND INSULIN-LIKE
GROWTH FACTOR 1 IN DNA REPAIR FIDELITY (Krzysztof Reiss, Kamel Khalili, and
Luis Del Valle). 5 INVOLVEMENT OF THE POLYOMAVIRUS, JC VIRUS, IN COLORECTAL
CANCER (C. Richard Boland, Luigi Ricciardiello, and Ajay Goel). 6 POSSIBLE
ASSOCIATION OF BK VIRUS WITH PROSTATE CANCER (Michael J. Imperiale and
Dweepanita Das). 7 ONCOGENIC TRANSFORMATION BY POLYOMAVIRUS LARGE T ANTIGEN
(Abhilasha V. Rathi and James M. Pipas). 8 SIMIAN VIRUS 40, HUMAN
INFECTIONS, AND CANCER: EMERGING CONCEPTS AND CAUSALITY CONSIDERATIONS
(Janet S. Butel). 9 SIMIAN VIRUS 40 AND MESOTHELIOMA (Natalya Baranova and
Michele Carbone). 10 MOLECULAR IMMUNOBIOLOGY OF HEPATITIS B-ASSOCIATED
VIRAL CANCER (Timothy M. Block and Anand S. Mehta). 11 HEPATITIS B VACCINE
AND HEPATOCELLULAR CARCINOMA (Mei-Hwei Chang and Ding-Shinn Chen). 12
PATHOGENESIS OF ACUTE AND CHRONIC HEPATITIS C VIRUS INFECTION (Mark A.
Feitelson, Helena M.G.P.V. Reis, Jingbo Pan, and Bill Sun). 13 MOLECULAR
MECHANISMS OF HEPATITIS C VIRUS-INDUCED CELLULAR TRANSFORMATION (Donna Sir
and Jing-Hsiung James Ou). 14 CLINICAL ASPECTS OF HTLV-1-ASSOCIATED CANCER
(Masao Matsuoka). 15 ONCOGENIC POTENTIAL OF THE HTLV-1 TAX PROTEIN (Susan
J. Marriott). 16 HIV-1-ASSOCIATED MALIGNANCY: BASIC AND CLINICAL ASPECTS
(Melissa Agsalda and Bruce Shiramizu). 17 HIV-RELATED LYMPHOMA (Giulia De
Falco, Cristiana Bellan, Stefano Lazzi, and Lorenzo Leoncini). 18 BIOLOGY
AND EPIDEMIOLOGY OF HHV-8 (Veenu Minhas and Charles Wood). 19 THE ROLE OF
KSHV IN PATHOGENESIS OF KAPOSI'S SARCOMA (Gary S. Hayward, Donald J.
Alcendor, and Ravit Arav-Boger). 20 MOLECULAR PATHOBIOLOGY OF EBV INFECTION
(Joseph S. Pagano). 21 EPSTEIN-BARR VIRUS AS A PATHOGEN (Wasim A. Dar and
Bill Sugden). Index.