Helmut Schenkel-Brunner

Human Blood Groups

Chemical and Biochemical Basis of Antigen Specificity

• Broschiertes Buch

Produktbeschreibung

This monograph covers the entire field of blood group serology, with its main emphasis on the chemical and biochemical basis of blood group specificity. Full consideration is given to molecular biology investigations, in particular to studies on the structure of blood group genes and the molecular biological basis of alleles and rare blood group variants, whereby relevant literature up to the year 2000 is covered. The text is supplemented by numerous illustrations and tables, and detailed reference lists. The five years since the publication of the first edition have brought further advances in blood group research. Thanks to modern molecular biology, scientists have not only been able to identify the bearer molecules of many more blood groups, they have clarified the molecular basis of a number of further blood group specifities as well. This book offers a concise survey for use by blood bankers and researchers in biochemistry, blood group serology, immunohematolo gy, forensic medicine, population genetics, and anthropology.

Produktdetails

• Verlag: Springer, Wien
• 2. Aufl.
• Seitenzahl: 640
• Erscheinungstermin: 14. Februar 2002
• Englisch
• Abmessung: 235mm
• Gewicht: 1380g
• ISBN-13: 9783211834718
• ISBN-10: 3211834710
• Artikelnr.: 06108544

Inhaltsangabe

INHALT LANG:
Introduction
Glycoconjugates
Glycolipids; Glycoproteins
Biosynthesis of Glycoconjugates
Biosynthesis of Glycoproteins; Biosynthesis of Glycosphingoliopids; Regulation of Chain Structure
Erythrocyte Membrane
Constituents of the Erythrocyte Membrane; Molecular Architecture of the Erythrocyte Membrane; Architecture of the Membranes of Nucleated Cells
ABO(H) System
Genetics; Antisera and Lectins; Blood Group ABH Substances; Biosynthesis of ABH Antigens and its Genetic Regulation; ABH Subgroups and Variants
Lewis System and the Antigens Lex and Ley
Genetics; Antisera and Lectins; Blood Group Lewis Substances; Biosynthesis of Blood Group Lewis Determinants; Antigens Lex and Ley
Antigens I and i
Antisera; Blood Group I and i Determinants; Blood Group I and i Substances; Expression of I and i Activity During Embryonic Development and under
Various Pathological Conditions; Biosynthesis of I and i Determinant Structures
P System
Antisera and Lectins; Blood Group P Substances;Biosynthesis of the Blood Group P Antigens
MNS System
Genetics; Antisera and Lectins; Blood Group MNS Substances; Structure and Organisation of the MNS Gene Complex; Chemical Structures of the Main
Determinants of the MNS System; Rare Variants of the MNS Antigens; MNS-Deficient Phenotypes, and Antigens Associated with MNS System
Polyagglutination
Antisera and Lectins; T Antigen; Tk Antigen; Th Antigen; Tx Antigen; Tn Antigen; VA and NOR
Sid and Cad
Antisera and Lectins; Sda Active Substances; Cad Active Substances; Investigations on the Biosynthesis of Sda and Cad Determinants
Slalic Acid-Containing Receptors for Cold Agglutinins
Antisera; Structures of Antigenic Determinants; Occurrence of Pr, Gd, and Sa Antigens on Other Cell Types; Other Receptors for Cold Agglutinins
Rh System
Genetics; Rh Antisera, Chemical Properties of Rh Antigens; Number of Rh Proteins; Molecular Biological Investigations; Rh Antigens and Phenotypes
Landsteiner-Wiener System
Chido / Rodgers System
Duffy System
Kell System
Antibodies; Kell-Deficient Phenotypes; Kell Glycoprotein; Kell Alleles; Kx Antigen
Gerbich System
Glycophorin C and Glycophorin D; The Antigen Characters Ge1, Ge2, Ge3, and Ge4, and the Lsa Determinant; Wb (Webb); Dha (Duch); Ana (Ahonen)
Lutheran System
Diego System
Antibodies; The Antigens of the Diego System
Cromer System
Dombrock System
Yt System
Indian System
Knops System
Kidd System
Xg System
Colton System
OK System
JMH Antigen
Antigens of the Major Histocompatibilitiy Complex (HLA Antigens)
Genetics; HLA Antisera; HLA Gene Products
HEMPAS
Carcinoembryonic Antigen (CEA) Family

Rezensionen

"... This book is well organized, accurate ... Helmut Schenkel-Brunner is to be congratulated on compiling and presenting the information in a clear and consice manner ... "Human blood groups: chemical and biochemical basis of antigen specificity is a useful reference book for the shelf of those interested in understanding the biochemical and genetical aspects of blood group antigens. Human Genetics 2001