Moyamoya Disease Update (eBook, PDF)

Redaktion: Cho, Byung-Kyu; Tominaga, Teiji

• Format: PDF

Produktbeschreibung

Moyamoya disease (MMD) was first reported as a new entity among vascular disorders in 1957. Named for the abnormal vascular networks found around the occluded distal internal carotid artery, it is the most common pediatric cerebrovascular disease in East Asia. In recent years large amounts of data on MMD have been collected and important investigations have been carried out in Japan and Korea, even as the pathophysiology of the disease remains to be discovered. This monograph covers a diversity of topics and presents a systematic compilation of the data and current status of MMD in clinical practice and basic research. With contributions by more than 70 authors, the book includes sections on genetics, computational analysis of hemodynamic shear stress, new imaging techniques, and endovascular treatment of MMD, along with practical applications and future directions for gene and stem cell therapies. For neurosurgeons as well as neurologists and pediatricians, this volume will help lead to more efficient and informed management of MMD.

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Produktdetails

• Verlag: Springer-Verlag GmbH
• Seitenzahl: 387
• Erscheinungstermin: 26. Februar 2010
• Englisch
• ISBN-13: 9784431997030
• Artikelnr.: 37411851

Inhaltsangabe

Introduction Overview (Teiji Tominaga) Pathology (Ken-ichiro Kikuta) Unilateral MMD (Chang Wan Oh) Moyamoya syndrome (Michael Scott) Epidemiology Overview (Norihiro Suzuki) Familial MMD (Joong-Uhn Choi) Genetics Overview (Akio Koizumi) Genetic linkage study (Akio Koizumi) SNP study (Hyun-Seung Kang) HLA study (Myoung Hee Park) Pathophysiology I (Protein, cell, and immunology) Overview (Seung-Ki Kim) bFGF and cytokines (Kiyohiro Houkin) Ischemia/angiogenesis-related molecules and cells (Jin Hyun Kim) Vascular smooth muscle cell-related molecules and cells (Yasushi Takagi) Immunology (Ji Hoon Phi) Pathophysiology II (Hemodynamics, Biomechanical aspect) Overview (Eun Bo Shim) Regional predilection of lesions and stages of MMD (Ho Jun Seol) Clinical features Overview (Yong-Seung Hwang) Headache (Reizo Shirane) Involuntary movement (Shigeru Nogawa) Progression of MMD (Norihiro Suzuki) Associated systemic arterial stenosis (Hae Il Cheong) Associated neurosurgical diseases (Izumi Nagata) Diagnostic evaluation Morphological imaging Overview (Young Chul Won) Pre- Postoperative MRA (Hiyohiro Houkin) MRI (Yukihiko Fujii) Functional imaging Overview (Joji Nakagawara) SPECT (Dong Soo Lee) Iomazenil-SPECT (BZP-receptor) (Joji Nakagawara) Perfusion MRI/CT (In-Won Kim) PET (Sunao Nariai) Electrophysiology EEG (Jong Hee Chae) MEG (Nobukazu Nakasato) Surgical technique Overview (Toshio Matsushima) Anesthesia and perioperative care (Hee Soo Kim) ACA territory reinforcement (Chae-Yong Kim) PCA territory reinforcement (Dal Soo Kim) Endovascular procedures (O Ki Kwon) Surgical outcome Overview (Byung-Kyu Cho) Risk factors for complication (Miki Fujimura) Cognition and quality of life (Satoshi Kuroda) Special consideration I Overview: Issues in young children and adults (Teiji Tominaga) MMD in the young (Kyu-Chang Wang) MMD in adult Management of hemorrhage (Susumu Miyamoto) Direct bypass surgery, postsurgical hyperperfusion syndrome (Jeong Eun Kim) Special consideration II Pregnancy/delivery in MMD (Jun Takahashi) Asymptomatic MMD (Satoshi Kuroda) Hyperthyroidism in MMD (So-Hyang Im) Enhancer of revascularization, gene and stem cell therapies (Isao Date) Special consideration III MMD in North America (Gary Steinberg) MMD in Europe (Sainte-Rose) MMD in Asia (Yong-Kwang Tu) Future perspectives of MMD (Byung-Kyu Cho).

Rezensionen

From the reviews:

"This is an almost 400-page book on the current status of all things relating to Moyamoya disease (MMD) definition, etiology, status of research, diagnostic modalities, and treatment options. ... Illustrative of all this material ... are well done, sharp, and clear, with good legends and explanatory material. ... Certainly, this is the definitive book for someone who wishes information on Moyamoya disease. It is quite complete, almost excessively so, and will undoubtedly remain a basic source for several years to come." (Robert M. Arensman, Doody's Review Service, June, 2010)

"Moyamoya Disease Update, edited by Cho and Tominaga, provides an excellent update of this recent progress and a comprehensive overview of all relevant aspects of the disease. ... This book is an exciting and highly recommended update on moyamoya disease. In addition to the scientific and clinical information, the book clearly indicates that recent years have been substantial progress in our understanding of the disease." (Peter Vajkoczy, The Lancet Neurology, Vol. 9, August, 2010)