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The sensory hair cells in the inner ear and vestibular system convert
mechanical stimuli, sound and motion into neural activity that is
responsible for the sensations of hearing, motion and head position.
In mammals, the loss of hair cells from acoustic overstimulation,
ototoxic drugs and aging is irreversible, leading to a permanent loss
of function. However, it is now clear that hair cells in other
vertebrates are capable of regenerating and recovering partial or
complete function. Moreover, partially damaged hair cells can undergo
self-repair or be protected from
…mehr

Produktbeschreibung
The sensory hair cells in the inner ear and vestibular system convert

mechanical stimuli, sound and motion into neural activity that is

responsible for the sensations of hearing, motion and head position.

In mammals, the loss of hair cells from acoustic overstimulation,

ototoxic drugs and aging is irreversible, leading to a permanent loss

of function. However, it is now clear that hair cells in other

vertebrates are capable of regenerating and recovering partial or

complete function. Moreover, partially damaged hair cells can undergo

self-repair or be protected from traumatic insults by external

compounds. This volume provides a comprehensive survey of what is

currently known about the regeneration, repair and protection of

sensory hair cells and subsequent recovery of function in the auditory

and vestibular system. The aim is to provide graduate students,

postdoctoral fellows, clinicians and scientists in related disciplines

with the biological bases of hair cells and with an understanding of

the factors that contribute to their regeneration and repair.
This book contains the papers that were presented at the XIIIth International Symposium on Hearing (ISH), which was held in Dourdan, France, between August 24 and 29, 2003. From its first edition in 1969, the Symposium has had a distinguished tradition of bringing together auditory psychologists and physiologists. Hearing science now also includes computational modeling and brain imaging, and this is reflected in the papers collected. The rich interactions between participants during the meeting were yet another indication of the appositeness of the original idea to confront approaches around shared scientific issues. A total of 62 solicited papers are included, organized into 12 broad thematic areas ranging from cochlear signal processing to plasticity and perceptual learning. The themes follow the sessions and the chronological order of the paper presentations during the symposium. A notable feature of the ISH books is the transcription of the discussions between participants. A draft version of the book is circulated before the meeting, and all participants are invited to make written comments, before or during the presentations. This particularity is perhaps what makes the ISH book series so valuable as a truthful picture of the evolution of issues in hearing science. We tried to uphold this tradition, which was all the easier because of the excellent scientific content of the discussions.
Autorenporträt
Daniel Pressnitzer, Ircam-CRNS, Paris, France / Alain de Cheveigne, Ircam-CRNS, Paris, France / Stephen McAdams, Ircam-CRNS, Paris, France / Lionel Collet, Universite Claude Bernard Lyon 1, France