RNA and DNA Diagnostics

Herausgegeben:Erdmann, Volker A.; Barciszewski, Jan

• Gebundenes Buch

Produktbeschreibung

The aim of molecular diagnostics is preferentially to detect a developing disease before any symptoms appear. There has been a significant increase, fueled by technologies from the human genome project, in the availability of nucleic acid sequence information for all living organisms including bacteria and viruses. When combined with a different type of instrumentation applied, the resulting diagnostics is specific and sensitive. Nucleic acid-based medical diagnosis detects specific DNAs or RNAs from the infecting organism or virus and a specific gene or the expression of a gene associated with a disease. Nucleic acid approaches also stimulate a basic science by opening lines of inquiry that will lead to greater understanding of the molecules at the center of life. One can follow Richard Feynman's famous statement "What I cannot create, I do not understand."

Produktdetails

• RNA Technologies
• Verlag: Springer / Springer International Publishing / Springer, Berlin
• Artikelnr. des Verlages: 978-3-319-17304-7
• 2015
• Seitenzahl: 360
• Erscheinungstermin: 29. Juni 2015
• Englisch
• Abmessung: 241mm x 160mm x 25mm
• Gewicht: 693g
• ISBN-13: 9783319173047
• ISBN-10: 3319173049
• Artikelnr.: 42390850

Inhaltsangabe

Electrochemical Biosensors for miRNA Detection.- Electrochemical Detection of RNA.- DNA and PNA probes for DNA Detection in Electroanalytical Systems.- DNA for Non-Nucleic Acid Sensing.- Aptamers in Oncotherapy.- Genotyping of Single Nucleotide Polymorphism.- Environmentally Responsive and Bright Fluorescent Probes Possessing Dansyl-modified Oligonucleotides under Hybridization of DNA and RNA.- Fluorescent Nucleic Acid Analogues in Research and Clinical Diagnostics.- Emergent Properties and Functions of Nanoconfined Nucleic Acid Architectures.- RNA and DNA Diagnostics on Microspheres: Current and Emerging Methods.- DNA and RNA Electronic Properties for Molecular Modifications and Environmental State Diagnostics.- Mechanochemical Sensing.- Microarrays as Research Tools and Diagnostic Devices.- Quadruplex Priming Amplification (QPA) for Nucleic Acid Diagnostics.- Single-molecule strategies for DNA and RNA diagnostics.- Detection and Assessment of microRNA Expression in Human Disease.