OCT in Central Nervous System Diseases
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This book reviews recent important advances in the use of optical coherence tomography (OCT) in order to analyze neurodegeneration within the retina through the quantification of axonal loss. Detailed information is provided on the role of OCT as a promising tool for the evaluation of disease progression in numerous neurodegenerative disorders and as a biological marker of neuroaxonal injury. The disorders considered include multiple sclerosis, Parkinson's disease, Alzheimer's disease, intracranial hypertension, Friedreich's ataxia, schizophrenia, hereditary optic neuropathies, glaucoma, and…mehr

Produktbeschreibung
This book reviews recent important advances in the use of optical coherence tomography (OCT) in order to analyze neurodegeneration within the retina through the quantification of axonal loss. Detailed information is provided on the role of OCT as a promising tool for the evaluation of disease progression in numerous neurodegenerative disorders and as a biological marker of neuroaxonal injury. The disorders considered include multiple sclerosis, Parkinson's disease, Alzheimer's disease, intracranial hypertension, Friedreich's ataxia, schizophrenia, hereditary optic neuropathies, glaucoma, and amblyopia. Individual chapters are also devoted to OCT technique, new OCT technology in neuro-ophthalmology, OCT and pharmacological treatment, and the use of OCT in animal models. By documenting the ability of OCT to provide key information on CNS diseases, this book illustrates convincingly that the eye is indeed the "window to the brain".
  • Produktdetails
  • Verlag: Springer, Berlin; Springer International Publishing
  • Artikelnr. des Verlages: 978-3-319-24083-1
  • 1st ed. 2016
  • Erscheinungstermin: Februar 2016
  • Englisch
  • Abmessung: 242mm x 164mm x 22mm
  • Gewicht: 570g
  • ISBN-13: 9783319240831
  • ISBN-10: 3319240838
  • Artikelnr.: 43439086
Autorenporträt
Andrzej Grzybowski, MD, PhD, is Professor of Ophthalmology and Chair of the Department of Ophthalmology, University of Warmia and Mazury, Olsztyn, Poland and Head of the Department of Ophthalmology at Poznan City Hospital, Poznan, Poland. His major areas of expertise are cataract surgery, presbyopia treatment, clear lens exchange, vitroretinal surgery, glaucoma pathogenesis, neuro-ophthalmology, and history of ophthalmology. Dr. Grzybowski is a member of the European University Professors of Ophthalmology (EUPO), an expert of the European Medicines Agency, an International Fellow of the American Academy of Ophthalmology, and an International Projects and Grants Reviewer for the College of Optometry, London. He is also acting as program coordinator for the World Congress of Ophthalmology in Tokyo in 2014. Dr. Grzybowski is the recipient of various awards, including the Bronze Cross of Merit from the President of Poland in 2008 and the Zakon Prize from the History of Dermatology Society in 2010 and 2011. He is involved in editorial work in collaboration with many prestigious journals, as associate editor (Acta Ophthalmologica), section editor (Clinics in Dermatology, Neuro-Ophthalmology), editor in chief (Archive of the History and Philosophy of Medicine), editorial board member (Saudi Journal of Ophthalmology), and reviewer (more than 20 journals). He is the author of more than 230 international peer-reviewed papers.
Inhaltsangabe
Introduction.- OCT Technique - Past, Present and Future.- Optic Disc Edema.- Compressive Optic Neuropathy.- Multiple Sclerosis.- Parkinson's Disease.- Alzheimer's Disease.- Friedreichs Ataxia and More.- Other Neurological Disorders: Migraine, Neurosarcoidosis, Schizophrenia, Obstructive Sleep Apnea-Hypopnea Syndrome (OSAHS).- Hereditary Optic Neuropathies.- Trans Neuronal Retrograde Degeneration.- New OCT Technology in Neuro-Ophthalmology.- OCT and Pharmacological Treatment.- Animal Models in Neuro-Ophthalmology.- OCT in Glaucoma.- OCT in Amblyopia.- Conclusions.
Rezensionen
"The book is useful for all (neuro)ophthalmologists, and neurologists interested in the optic neuropathies and more generalized neurodegeneration. ... OCT technology enables accurate measurement of the important retinal structures involved in CNS diseases, and the present book helps the reader to find his/her way through the important findings based on OCT studies. These findings are certainly helpful in the diagnostic work-up of these patients, but perhaps as yet are not sensitive enough." (Frank Verbraak, Graefe's Archive for Clinical and Experimental Ophthalmology, Vol. 255, 2017)