Take advantage of new insights into prevention, diagnosis and treatment of coronary heart disease in women -- to the benefit of your patients. Designed to optimize your daily practice, this book gives lucid, up-to-date answers to numerous questions: What are the risks and benefits of hormone replacement therapy? What are the major risk factors for coronary heart disease in women? What are the most appropriate diagnostic tests in women? Which is the better treatment option for the woman with myocardial infarction -- lysis or primary angioplasty?…mehr
Take advantage of new insights into prevention, diagnosis and treatment of coronary heart disease in women -- to the benefit of your patients. Designed to optimize your daily practice, this book gives lucid, up-to-date answers to numerous questions:
What are the risks and benefits of hormone replacement therapy?
What are the major risk factors for coronary heart disease in women?
What are the most appropriate diagnostic tests in women?
Which is the better treatment option for the woman with myocardial infarction -- lysis or primary angioplasty?
Elisabeth von der Lohe, Wishard Health Services, Indianapolis, IN, USA
'1 Epidemiology.- Definition.- Gender-Specific Mortality Rates.- Morbidity and Mortality with Respect to Age and Gender.- Perception.- Mortality in Myocardial Infarction: Comparison Between Women and Men.- International Comparisons.- The "MONItoring Cardiovascular Disease" Project of the WHO (WHO MONICA Project).- 2 Cardiovascular Risk Factors and the Development of Coronary Heart Disease in Women Smoking.- Smoking.- Dyslipidemia.- Lipoprotein (a).- Diabetes Mellitus.- Insulin Resistance and Polycystic Ovary Syndrome.- Family History of Coronary Heart Disease or Genetic Disposition.- Hypertension.- Sedentary Lifestyle.- Obesity.- Homocysteine.- High sensitivity C-reactive Protein.- Risk Factors Unique to Women.- Menopause.- Oral Contraception.- 3 Pathophysiology of Coronary Heart Disease and the Effects of Estrogen.- Basics.- Plaque Formation and Significance of Plaques in CHD.- Effects of Estrogen.- Effect of Estrogen on Vascular Reactivity and Endothelial Function.- Effect of Estrogen on Lipid Metabolism.- Antioxidative Effect of Estrogen.- Effect of Estrogen on Inflammation.- Effect of Estrogen on Hemostasis.- 4 Stable Angina.- Definition and Pathophysiology of Angina Pectoris.- Diagnosis Based on Symptoms.- Prinzmetal's or Variant Angina.- Syndrome X.- Diagnostic Evaluation.- Electrocardiogram.- Stress Testing, Including Stress Echocardiography and Nuclear Imaging.- Determination of Pretest Probability for CHD.- Selection of Stress Test.- Stress ECG.- Nuclear Imaging.- Stress Echocardiography.- Pharmacological Stress Tests.- Electron Beam Computed Tomography.- Magnetic Resonance Imaging.- Diagnostic Cardiac Catheterization.- Gender Differences in the Use of Diagnostic Cardiac Catheterizations and Percutaneous Coronary Intervention.- Medical Management.- Beta-blockers.- Nitrate.- Calcium Channel Blockers.- Percutaneous Coronary Intervention for Stable Angina.- Gender-Specific Success and Complication Rates for Balloon Angioplasty.- Gender-Specific Success and Complication Rates for Coronary Intervention with Stent Implantation.- Restenosis.- Rotablator Therapy, Directional Coronary Atherectomy, Laser Therapy.- Multivessel Coronary Intervention - When PCI? When Bypass Surgery?.- 5 Acute Myocardial Infarction.- Progression from Stable Coronary Heart Disease to Myocardial Infarction.- Epidemiology of Acute Myocardial Infarction.- Pathophysiology.- Clinical Presentation of Acute Myocardial Infarction.- Silent Myocardial Infarction.- Symptomatic Myocardial Infarction.- Criteria for the Diagnosis of Acute Myocardial Infarction.- Clinical Presentation.- Electrocardiogram.- Serum Markers of Cardiac Damage.- Creatine Kinase and the CK Isoenzyme CK-MB.- Troponin T and I.- Therapy.- Revascularization.- Thrombolytic Therapy.- Primary Percutaneous Transluminal Coronary Angioplasty.- Thrombolysis Versus Primary PTCA.- Rescue PTCA after Thrombolysis of Acute Myocardial Infarction.- Medical Therapy of Acute Myocardial Infarction.- Aspirin.- Beta-blockers.- Unfractionated Heparin.- Calcium Channel Blockers.- ACE Inhibitors.- Nitrates.- Complications.- Prognosis.- Mortality in Acute Myocardial Infarction (With and Without Thrombolysis).- Mortality in the Pre-thrombolytic Era (Mid-1960s to Early-1980s).- Mortality in the Thrombolytic Era (1980 to Present).- Influence of Gender on the Referral for Coronary Angiography in Patients with Acute Myocardial Infarction.- 6 Acute Coronary Syndromes.- Non-ST-Elevation Myocardial Infarction/Unstable Angina.- Definition.- Presentation.- Diagnosis.- Therapy.- Medical Therapy.- Aspirin.- Unfractionated Heparin.- Low-Molecular-Weight Heparin.- Glycoprotein IIb/IIIa Receptor Antagonists.- Nitrates.- Beta-blocker.- Calcium Channel Blocker.- Interventional Therapy.- 7 Coronary Artery Bypass Surgery.- Operative Mortality.- Complications Associated with CABG.- Long-Term Outcomes.- Indication for CABG Surgery.- Comp
From the reviews:
"This book gives a basic complete review of coronary artery disease (CAD) ... . it is useful for students, residents and primary care physicians. ... The best feature of the book is the concise, current and complete review of CAD management which makes it very useful for students and residents. The other nice feature is a complete review of the HRT trials and studies. Assessment: Overall, the book provides a good review of CAD management for men and women ... ." (Thriveni Sanagala, www.doody.com, February, 2004)
"The text aims to cover broad areas related to coronary heart disease. ... The book is generally well set out and benefits from the summaries at the end of each chapter. There are several graphical illustrations that break up the text satisfactorily. Each chapter is well referenced, providing the opportunity to examine, the subject more comprehensively. In summary, this is an interesting book ... . It would appeal to cardiologists with a particular interest in gender-specific differences in ischaemic heart disease." (Interventional Cardiology Monitor, Vol. 10 (4), 2003)
"The book is easy to read and studies all aspects of coronary heart disease ... . For each chapter, an overview of the actual knowledge is clearly presented and discussed with special emphasis on gender specificity. Keynotes are highlighted and a summarizing paragraph concludes each chapter. ... I would recommend the reading of this book to all cardiologists who are interested in an accurate synthesis of the most recent data about an emerging subject: coronary artery disease in women." (Agnès Pasquet, Acta Cardiologica, Vol. 59 (3), 2004)