Drug Efficacy, Safety, and Biologics Discovery
Emerging Technologies and Tools
Herausgegeben von Ekins, Sean; Xu, Jinghai J.
Drug Efficacy, Safety, and Biologics Discovery
Emerging Technologies and Tools
Herausgegeben von Ekins, Sean; Xu, Jinghai J.
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Drug Efficacy, Safety, and Biologics Discovery: Emerging Technologies and Tools covers key emerging technologies in pharmaceutical R & D and how they have substantially impacted (or are currently impacting) drug discovery. The cross disciplinary collaborations implicit in integrating these technologies with drug discovery operations will fuel the engine for future innovations. This book cuts across the multiple areas of drug discovery, each chapter authored by pioneers in that field, making for a broad appeal to the chemical and biological scientists and technologists involved in drug discovery and development.…mehr
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- Produktdetails
- Wiley Series on Technologies for the Pharmaceutical Industry
- Verlag: Wiley & Sons
- 1. Auflage
- Seitenzahl: 400
- Erscheinungstermin: 14. Januar 2009
- Englisch
- Abmessung: 236mm x 163mm x 26mm
- Gewicht: 701g
- ISBN-13: 9780470225554
- ISBN-10: 0470225556
- Artikelnr.: 25427354
- Wiley Series on Technologies for the Pharmaceutical Industry
- Verlag: Wiley & Sons
- 1. Auflage
- Seitenzahl: 400
- Erscheinungstermin: 14. Januar 2009
- Englisch
- Abmessung: 236mm x 163mm x 26mm
- Gewicht: 701g
- ISBN-13: 9780470225554
- ISBN-10: 0470225556
- Artikelnr.: 25427354
Efficacy and Toxicity (Leonidas G. Alexopoulos
Julio Saez-Rodriguez and Christopher W. Espelin). 3. Cellular Systems Biology Applied to Pre-Clinical Safety Testing: A Case Study of CellCiphr(TM) Profiling (Lawrence Vernetti
William Irwin
Kenneth A. Giuliano
Albert Gough
Kate Johnston and D. Lansing Taylor). 4. Systems Pharmacology
Biomarkers and Biomolecular Networks (Aram Adourian
Thomas N. Plasterer
Raji Balasubramanian
Ezra Jennings
Shunguang Wang
Jan van der Greef
Robert McBurney
Pieter Muntendam
and Noubar Afeyan). 5. Zebrafish Models for Human Diseases and Drug Discovery (Hanbing Zhong
Ning-Ai Liu and Shuo Lin). 6. Toxicity Pathways and Models: Mining for Potential Side Effects (Sean Ekins and Josef Scheiber). 7. Computational Systems Biology Modeling of Dosimetry and Cellular Response Pathways (Qiang Zhang
Yu-Mei Tan
Sudin Bhattacharya and Melvin E. Andersen). 8. Stem Cell Technology for Embryotoxicity
Cardiotoxicity and Hepatotoxicity Evaluation (Julio C. Davila
Donald B. Stedman
Sandra J. Engle
Howard I. Pryor II and Joseph P. Vacanti). 9. Telemetry Technology for Preclinical Drug Discovery and Development (Yi Yang). PART II. BIOLOGICS TECHNOLOGY. 10. Nanotechnology to Improve Oral Drug Delivery (Mayank D. Bhavsar
Shardool Jain
and Mansoor M. Amiji). 11. Functional Glycomics and the Future of Glycomic Drugs (Ram Sasisekharan). 12. Modeling Efficacy and Safety of Engineered Biologics (Jeff Chabot and Bruce Gomes). 13. Regulation of Gene Expression by Small
Non-Coding RNAs: Practical Applications (Roman Herrara and Eric Tien). PART III. FUTURE PERSPECTIVE. 14. Future Perspectives of Biological Engineering in Pharmaceutical Research: The Paradigm of Modeling
Mining
Manipulation and Measurements (Jinghai J. Xu
Sean Ekins
Michael McGlashen and Douglas Lauffenburger). Index.
Efficacy and Toxicity (Leonidas G. Alexopoulos
Julio Saez-Rodriguez and Christopher W. Espelin). 3. Cellular Systems Biology Applied to Pre-Clinical Safety Testing: A Case Study of CellCiphr(TM) Profiling (Lawrence Vernetti
William Irwin
Kenneth A. Giuliano
Albert Gough
Kate Johnston and D. Lansing Taylor). 4. Systems Pharmacology
Biomarkers and Biomolecular Networks (Aram Adourian
Thomas N. Plasterer
Raji Balasubramanian
Ezra Jennings
Shunguang Wang
Jan van der Greef
Robert McBurney
Pieter Muntendam
and Noubar Afeyan). 5. Zebrafish Models for Human Diseases and Drug Discovery (Hanbing Zhong
Ning-Ai Liu and Shuo Lin). 6. Toxicity Pathways and Models: Mining for Potential Side Effects (Sean Ekins and Josef Scheiber). 7. Computational Systems Biology Modeling of Dosimetry and Cellular Response Pathways (Qiang Zhang
Yu-Mei Tan
Sudin Bhattacharya and Melvin E. Andersen). 8. Stem Cell Technology for Embryotoxicity
Cardiotoxicity and Hepatotoxicity Evaluation (Julio C. Davila
Donald B. Stedman
Sandra J. Engle
Howard I. Pryor II and Joseph P. Vacanti). 9. Telemetry Technology for Preclinical Drug Discovery and Development (Yi Yang). PART II. BIOLOGICS TECHNOLOGY. 10. Nanotechnology to Improve Oral Drug Delivery (Mayank D. Bhavsar
Shardool Jain
and Mansoor M. Amiji). 11. Functional Glycomics and the Future of Glycomic Drugs (Ram Sasisekharan). 12. Modeling Efficacy and Safety of Engineered Biologics (Jeff Chabot and Bruce Gomes). 13. Regulation of Gene Expression by Small
Non-Coding RNAs: Practical Applications (Roman Herrara and Eric Tien). PART III. FUTURE PERSPECTIVE. 14. Future Perspectives of Biological Engineering in Pharmaceutical Research: The Paradigm of Modeling
Mining
Manipulation and Measurements (Jinghai J. Xu
Sean Ekins
Michael McGlashen and Douglas Lauffenburger). Index.