Patricia L. Keen, Mark H. M. M. Montforts

Antimicrobial Resistance in the Environment (eBook, PDF)

• Format: PDF

Produktbeschreibung

Examines effects of the environmental distribution of antimicrobial resistance genes on human health and the ecosystem Resistance genes are everywhere in nature--in pathogens, commensals, and environmental microorganisms. This contributed work shows how the environment plays a pivotal role in the development of antimicrobial resistance traits in bacteria and the distribution of resistant microbial species, resistant genetic material, and antibiotic compounds. Readers will discover the impact of the distribution in the environment of antimicrobial resistance genes and antibiotics on both the ecosystem and human and animal health. Antimicrobial Resistance in the Environment is divided into four parts: * Part I, Sources, including ecological and clinical consequences of antibiotic resistance by environmental microbes * Part II, Fate, including strategies to assess and minimize the biological risk of antibiotic resistance in the environment * Part III, Antimicrobial Substances and Resistance, including antibiotics in the aquatic environment * Part IV, Effects and Risks, including the effect of antimicrobials used for non-human purposes on human health Recognizing the intricate links among overlapping complex systems, this book examines antimicrobial resistance using a comprehensive ecosystem approach. Moreover, the book's multidisciplinary framework applies principles of microbiology, environmental toxicology, and chemistry to assess the human and ecological risks associated with exposure to antibiotics or antibiotic resistance genes that are environmental contaminants. Each chapter has been written by one or more leading researchers in such fields as microbiology, environmental science, ecology, and toxicology. Comprehensive reference lists at the end of all chapters serve as a gateway to the primary research in the field. Presenting and analyzing the latest findings in a field of growing importance to human and environmental health, this text offers readers new insights into the role of the environment in antimicrobial resistance development, the dissemination of antimicrobial resistant genetic elements, and the transport of antibiotic resistance genes and antibiotics.

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Produktdetails

• Verlag: John Wiley & Sons
• Seitenzahl: 624
• Erscheinungstermin: 30. November 2011
• Englisch
• ISBN-13: 9781118156216
• Artikelnr.: 37340744

Autorenporträt

Patricia Lynn Keen, Ph.D. received her doctorate in Resource Management Environmental Studies from the University of British Columbia. Mark H.M.M. Montforts, Ph.D. is a Senior Policy Officer and Project Leader with The National Institute for Public Health and the Environment in The Netherlands. He is also a member of many other organizations such as the Dutch Biocides Expertise Network, the Working Group on Ecotoxicology of the EU Committee for Human Medicinal Products (CHMP) at the European Medicines Agency (EMEA), and the Scientific Advisory Board of the National Asthma Foundation.

Inhaltsangabe

PREFACE xi CONTRIBUTORS xv PART I SOURCES 1 Chapter 1 Introduction 3 Stuart
B. Levy Chapter 2 Path to Resistance 7 Vivian Miao, Dorothy Davies, and
Julian Davies Chapter 3 Antibiotic Resistome: A Framework Linking the
Clinic and the Environment 15 Gerard D. Wright Chapter 4 Ecological and
Clinical Consequences of Antibiotic Subsistence by Environmental Microbes
29 Gautam Dantas and Morten O. A. Sommer Chapter 5 Importance of Adaptive
and Stepwise Changes in the Rise and Spread of Antimicrobial Resistance 43
Lucia Fernandez, Elena B. M. Breidenstein, and Robert E. W. Hancock Chapter
6 Environmental Reservoirs of Resistance Genes in Antibiotic-Producing
Bacteria and Their Possible Impact on the Evolution of Antibiotic
Resistance 73 Paris Laskaris, William H. Gaze and Elizabeth M. H.
Wellington Chapter 7 Mechanisms of Bacterial Antibiotic Resistance and
Lessons Learned from Environmental Tetracycline-Resistant Bacteria 93
Marilyn C. Roberts Chapter 8 Environmental Antibiotic Resistome: New
Insights from Culture-Independent Approaches 123 Isabel S. Henriques, Artur
Alves, Maria Jose Saavedra, Mark H. M. M. Montforts, and Antonio Correia
PART II FATE 149 Chapter 9 Environmental Pollution by Antibiotic Resistance
Genes 151 Jose Luis Martinez and Jorge Olivares Chapter 10 Quantifying
Anthropogenic Impacts on Environmental Reservoirs of Antibiotic Resistance
173 Amy Pruden and Mazdak Arabi Chapter 11 Antibiotic Resistance in
Swine-Manure-Impacted Environments 203 Joanne Chee-Sanford, Scott Maxwell,
Kristy Tsau, Kelly Merrick, and Rustam Aminov Chapter 12
Antimicrobial-Resistant Indicator Bacteria in Manure and the Tracking of
Indicator Resistance Genes 225 Christina S. Hölzel and Karin Schwaiger
Chapter 13 Municipal Wastewater as a Reservoir of Antibiotic Resistance 241
Timothy Lapara and Tucker Burch Chapter 14 Strategies to Assess and
Minimize the Biological Risk of Antibiotic Resistance in the Environment
251 Thomas Schwartz Chapter 15 Antibiotic Resistance in Animals--The
Australian Perspective 265 Olasumbo Ndi and Mary Barton PART III
ANTIMICROBIAL SUBSTANCES AND RESISTANCE 291 Chapter 16 Detection and
Occurrence of Antibiotics and Their Metabolites in Pig Manure in Bavaria
(Germany) 293 Katrin Harms and Johann Bauer Chapter 17 Fate and Transport
of Antibiotics in Soil Systems 309 Alistair B. A. Boxall Chapter 18
Antibiotics in the Aquatic Environment 325 Klaus Kümmerer Chapter 19
Residues of Veterinary Drugs in Wild Fish 337 Thomas Heberer Chapter 20
Role of Quaternary Ammonium Compounds on Antimicrobial Resistance in the
Environment 349 Ulas Tezel and Spyros G. Pavlostathis PART IV EFFECTS AND
RISKS 389 Chapter 21 Human Health Importance of use of Antimicrobials in
Animals and Its Selection of Antimicrobial Resistance 391 Scott A. McEwen
Chapter 22 Antimicrobial Resistance Associated with Salmonid Farming 423
Claudio D. Miranda Chapter 23 Effect of Veterinary Medicines Introduced via
Manure into Soil on the Abundance and Diversity of Antibiotic Resistance
Genes on Their Transferability 453 Holger Heuer, Christoph Kopmann, Ute
Zimmerling, Ellen Krögerrecklenfort, Kristina Kleineidamm, Michael
Schloter, Eva M. Top and Kornelia Smalla Chapter 24 Tracking Antibiotics
and Antibiotic Resistance Genes through the Composting Process and Field
Distribution of Poultry Waste: Lessons Learned 465 Patricia L. Keen and
Nancy De With Chapter 25 Environmental Microbial Communities Living Under
Very High Antibiotic Selection Pressure 483 Anders Janzon, Erik
Kristiansson, and D. G. Joakim Larsson Chapter 26 Antibiotic Use During an
Influenza Pandemic: Downstream Ecological Effects and Antibiotic Resistance
503 Andrew C. Singer and Heike Schmitt Chapter 27 Use of Veterinary
Antibacterial Agents in Europe and the United States 539 Ingeborg M. van
Geijlswijk, Nico Bondt, Linda F. Puister-Jansen, and Dik J. Mevius Chapter
28 Regulatory Research on Antimicrobial Resistance in the Environment 549
Emily A. McVey and Mark H. M. M. Montforts INDEX 569