Food Chemical Hazard Detection (eBook, ePUB)

Development and Application of New Technologies
Redaktion: Wang, Shuo

• Format: ePub

Produktbeschreibung

Food chemical safety remains a serious concern to the food industry. Risks such as adulteration, the existence of toxic and allergenic compounds in foods, and poor regulation of postharvest processing indicate that food chemical safety is not fully guaranteed. With the increasing trend of globalization in the import and export of food products, the importance of employing accurate and reliable analytical instruments to rapidly detect chemical hazards in foods has become paramount. In recent years, many new applications for using a range of analytical methods to detect food chemical hazards have emerged. Food Chemical Hazard Detection: Development and Application of New Technologies aims to cover the major developments and applications in this field. With a far-reaching scope, this book includes sections dedicated to chromatography tandem mass spectrometry, immunoassay, biophotonics, nanotechnology, biosensors and microfluidic based "lab-on-a-chip". A team of expert authors from major academic institutions in the USA, Canada and China bring a wealth of research experiences to bear in this major new work, which will be required reading for anyone interested in food chemical hazards and their effective detection and intervention strategies. Food Chemical Hazard Detection: Development and Application of New Technologies is aimed at a diverse audience, including food safety testing laboratories, scientists and managers in the global food supply chain, academic institutions, governmental regulatory agencies and food safety training providers. Readers will receive not only the fundamentals about different detection techniques, but will also gain insights into the current and future applications of each technique.

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Produktdetails

• Verlag: John Wiley & Sons
• Seitenzahl: 344
• Erscheinungstermin: 26. Februar 2014
• Englisch
• ISBN-13: 9781118488560
• Artikelnr.: 44449257

Autorenporträt

Professor Shuo Wang is President of Tianjin University of Science and Technology, Director of Key Laboratory of Food Nutrition and Safety, Ministry of Education of China, and Cheung Kong Scholar. He is also the recipient of Chinese National Science Fund for Distinguished Young Scholars in 2012.

Inhaltsangabe

List of contributors xi Preface xiii Section I CHROMATOGRAPHY-TANDEM MASS
SPECTROMETRY 1 1 Recent developments in gas chromatography-mass
spectrometry for the detection of food chemical hazards 3 Renbang Zhao 3
1.1 The combination of gas chromatography and mass spectrometry 3 1.1.1
Introduction 3 1.1.2 Basic gas chromatography 4 1.1.3 Typical mass
analyzers and MS detectors in GC-MS 5 1.1.4 New development in GC-MS and
sample preparation 6 1.2 Analysis of pesticide residues in foods 8 1.2.1
Sample preparation 8 1.2.2 Development of GC-MS methods for the
determination of pesticides in foods 12 1.3 Analysis of contaminants formed
during food processing 18 1.3.1 Acrylamide 18 1.3.2 Heterocyclic amines 20
1.3.3 Furan 22 1.3.4 Polycyclic aromatic hydrocarbons (PAHs) 25 1.3.5
Tetramine 27 1.3.6 Chloropropanols 27 1.4 Analysis of environmental
contaminants 30 1.4.1 Organometallic compounds 30 1.4.2 Polychlorinated
biphenyls 31 1.4.3 Monocyclic aromatic hydrocarbons 34 1.5 Analysis of
contaminants from packaging materials 35 1.6 Nitrite 39 Summary 40
Abbreviations 40 References 41 2 Recent developments in liquid
chromatography-mass spectrometry for the detection of food chemical hazards
53 Hongyan Zhang and Jinxing He 53 2.1 Introduction to food safety
detection by liquid chromatography-mass spectrometry 53 2.2 Principles and
current technology of LC-MS 55 2.2.1 Extraction and/or purification of
specific analytes in food samples 55 2.2.2 Typical LC conditions for LC-MS
analysis 56 2.2.3 Mass spectrometry 57 2.2.4 Interface technology 58 2.2.5
Method validation and matrix effects 59 2.3 Applications of LC-MS in food
safety detection 60 2.3.1 Applications of LC-MS in the analysis of
veterinary drugs and growth-promoting agents 60 2.3.2 Applications of LC-MS
in the analysis of pesticide residue in foods 79 2.3.3 Applications of
LC-MS in the analysis of biotoxins in foods 84 2.4 Conclusion 87
Abbreviations 87 References 89 Section II IMMUNOASSAYS 103 3 State of the
art immunoassay developments and application to food chemical hazards 105
Xianghong Wang 105 3.1 Development and use of immunoassay to monitor food
chemical hazards 105 3.1.1 Chemical hazards in foods 105 3.1.2 Development
of immunoassay in the detection of food chemical hazards 107 3.2 Design and
synthesis of haptens 108 3.3 Antibody production 112 3.3.1 Elementary
knowledge of antibodies 112 3.3.2 Antibody classification 113 3.4
Immunoassay formats 115 3.4.1 Antigen-antibody reaction 115 3.4.2
Immunoassay classification 120 3.5 Sample preparation from various matrices
126 3.6 Conclusion 127 References 128 4 Molecularly imprinted polymers
(MIPs) - an emerging technique for chemical hazard determination 137
Qiliang Deng and Shuo Wang 137 4.1 Introduction 137 4.2 Preparation of
molecularly imprinted polymers 138 4.2.1 Template molecule 140 4.2.2
Functional monomer 140 4.2.3 Cross-linker monomer 141 4.2.4 Solvents 142
4.2.5 Initiator 143 4.2.6 Polymerization technique 143 4.3 Molecularly
imprinted solid-phase extraction modes 145 4.3.1 Off-line mode 146 4.3.2
On-line mode 147 4.4 Applications of MISPE in food chemical hazard
determination 148 4.4.1 Determination of drug residues 148 4.4.2
Determination of pesticides 155 4.4.3 Determination of herbicides 156 4.4.4
Determination of additives 158 4.4.5 Determination of environmental
contaminants 161 4.5 Conclusion and outlook 161 References 162 Section III
BIOPHOTONICS 173 5 Recent developments in infrared spectroscopy for the
detection of food chemical hazards 175 Xiaonan Lu 175 5.1 A brief
introduction to infrared spectroscopy and its application in the food
industry 175 5.2 Application of IR spectroscopy to detect chemical
adulterants in foods 177 5.3 Application of IR spectroscopy to detect
mycotoxins in foods 178 5.4 Application of IR spectroscopy to detect
pesticides in foods 181 5.5 Application of IR spectroscopy to detect
antibiotic residues in foods 181 5.6 Tips for reporting results 182 5.7
Trends in IR instrumentation 184 5.8 Trends in further applications of
chemometrics to analyze IR spectra 186 5.9 Conclusion 186 References 186 6
Recent developments in Raman spectroscopy for the detection of food
chemical hazards 191 Lili He 191 6.1 Introduction 191 6.1.1 Raman theory
191 6.1.2 Raman instrumentation and data analysis 192 6.1.3
Surface-enhanced Raman spectroscopy 193 6.2 Detection of chemicals in
simple solvents 194 6.3 Detection of chemicals in food matrices 196 6.3.1
Detection of small chemical molecules in food matrices 196 6.3.2 Detection
of large protein molecules in food matrices 199 6.4 Conclusion and outlook
203 References 204 Section IV NANOTECHNOLOGY 207 7 Engineered nanoparticles
(ENPs): applications, risk assessment, and risk management in the
agriculture and food sectors 209 Mahmoudreza Ovissipour, Syamaladevi M.
Roopesh, Barbara A. Rasco and Shyam S. Sablani 209 7.1 Introduction 209 7.2
Naturally occurring nanoparticles 211 7.3 Nanoparticle engineering 213 7.4
Engineered nanoparticles (ENPs) 214 7.5 Applications of ENPs in the
agriculture and food sectors 216 7.5.1 Applications of ENPs in agriculture
217 7.5.2 Antimicrobial applications of ENPs 223 7.5.3 Applications of
encapsulated ENPs in foods 225 7.5.4 Applications of ENPs in food packaging
225 7.6 Nanosensors 227 7.7 Impacts of ENPs on the environment 228 7.8 Risk
assessment and risk management of ENPs in food technology 233 7.9 Future
trends 235 References 236 8 Nanotechnology and its applications to improve
the detection of chemical hazards in foods 249 Mengshi Lin 249 8.1
Introduction 249 8.2 Nanomaterials used in sensors 250 8.3 Chemical hazards
in foods 251 8.3.1 Pesticides 251 8.3.2 Veterinary drugs 253 8.3.3
Bisphenol A 255 8.3.4 Melamine 256 8.3.5 Acrylamide 258 8.4 Conclusion 258
References 258 Section V BIOSENSORS 263 9 Microfluidics "lab-on-a-chip"
system for food chemical hazard detection 265 Jie Xu 265 9.1 Microfluidics
and "lab-on-a-chip" 265 9.2 Fluid mechanics at the microscale 266 9.3
Microfabrication technologies 269 9.4 Detection techniques 272 9.5
Representative applications in the detection of chemical hazards in foods
272 9.6 Future perspectives 279 References 280 10 Colorimetric biosensor
for food chemical hazards detection 291 Jianlong Wang and H. Susan Zhou 291
10.1 Introduction 291 10.2 Detection of hazardous chemicals in foods using
colorimetric biosensors based on bio-nanomaterials 293 10.2.1 Colorimetric
detection of pesticides 295 10.2.2 Colorimetric detection of veterinary
drugs 298 10.2.3 Colorimetric detection of heavy metal ions 301 10.2.4
Colorimetric detection of food additives 303 10.2.5 Colorimetric detection
of toxins 305 10.2.6 Colorimetric detection of other hazardous chemical
contaminants 305 10.3 Conclusion 306 Acknowledgments 307 References 307
Index 315