Curtis L. Meinert

Clinical Trials Dictionary (eBook, PDF)

Terminology and Usage Recommendations

• Format: PDF

Produktbeschreibung

A thoroughly updated new edition of the essential reference on the design, practice, and analysis of clinical trials Clinical Trials Dictionary: Terminology and Usage Recommendations, Second Edition presents clear, precise, meticulously detailed entries on all aspects of modern-day clinical trials. Written and compiled by one of the world's leading clinical trialists, this comprehensive volume incorporates areas of medicine, statistics, epidemiology, computer science, and bioethics--providing a treasure trove of key terms and ideas. This new edition continues to supply readers with the A-Z terminology needed to design, conduct, and analyze trials, introducing a vocabulary for the characterization and description of related features and activities. More than 300 new entries are now included, reflecting the current usage practices and conventions in the field, along with usage notes with recommendations on when to use the term in question. Detailed biographical notes highlight prominent historical figures and institutions in the field, and an extensive bibliography has been updated to provide readers with additional resources for further study. The most up-to-date work of its kind, Clinical Trials Dictionary, Second Edition is an essential reference for anyone who needs to report on, index, analyze, or assess the scientific strength and validity of clinical trials.

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Produktdetails

• Verlag: John Wiley & Sons
• Seitenzahl: 448
• Erscheinungstermin: 7. August 2012
• Englisch
• ISBN-13: 9781118315262
• Artikelnr.: 37352085

Autorenporträt

CURTIS L. MEINERT, PhD, is Professor in the Departments of Epidemiology and Biostatistics at the Johns Hopkins Bloomberg School of Public Health, where he served as founder of the Johns Hopkins Center for Clinical Trials. He is a Fellow of the American College of Epidemiology, the American Association for the Advancement of Science, the American Heart Association, and the Society for Clinical Trials. Dr. Meinert has focused his research on the methodological issues in clinical trials, including their design, conduct, policy, and practice. He is the author of Clinical Trials Handbook: Design and Conduct (Wiley).

Inhaltsangabe

FOREWORD 1ST EDITION ix PREFACE xi CONTRIBUTORS xiii EXPLANATORY NOTES xv
Domain of coverage xv Order and place of entries xv Synonyms, antonyms, and
related terms xv Language and usage conventions xv Sources and references
xvi Adages xvi Usage notes xvi Etymologies xvi Abbreviations xvii Index
xvii USAGE PRACTICES, CAUTIONS, AND RECOMMENDATIONS xix Recommended and
preferred usages xx Comparative and relative terms xxii Redundancies,
repetitions, and unnecessary words xxiii Not saying what we mean xxv
Humanizing the inanimate xxv Pre-, post-, non-, and un- words xxvi Small
troublesome words xxvi The language of praise, implied value judgment, and
presumption xxvii Euphemisms xxix Currency words xxix The language of
criticism xxx The language of exception xxxi The language of intimidation,
implication, and position xxxii The language of division xxxiii Usurpative
language xxxiii The language of positivity and negativity xxxiv Pronouns
xxxvii The language of equivocation and weaseling xxxvii Vacuous language
and claims xxxviii Jargon xxxviii Truth by declaration and repetition xxxix
ABBREVIATIONS xli LISTING OF ENTRIES xlvii Dictionary A 1 B 15 C 27 D 63 E
79 F 93 G 107 H 113 I 119 J and K 137 L 141 M 151 N 165 O 175 P 185 Q 217 R
221 S 241 T 273 U 291 V 297 W 301 X, Y, and Z 305 REFERENCES 307 INDEX 317
EQUATIONS AND FUNCTIONS Bayes' theorem 18 Binomial distribution 22 Binomial
theorem 22 Bivariate normal distribution 23 Exponential distribution 90
F-test statistic 93 Gamma distribution 107 Gamma function 107 Geometric
distribution 108 Gompertz's curve 108 Greco-Latin square 110 Hypergeometric
distribution 117 Inverse sine transformation 133 Kappa statistic 138
Kendall's tau 139 Latin square 141 Normal distribution 172 Poisson
distribution 199 Square root transformation 256 t distribution 273 GRAPHIC
ILLUSTRATIONS Figure 1. Bar Diagram 16 Figure 2. Bell-Shaped Curve 18
Figure 3. Bimodal Distribution 21 Figure 4. Box Plot 25 Figure 5.
Chi-square Distribution 31 Figure 6. Circle Graph 32 Figure 7. Closed
Sequential Design 37 Figure 8. CONSORT Chart 52 Figure 9. Cumulative
Frequency Distribution 60 Figure 10. Exponential Distribution 90 Figure 11.
F Distribution 93 Figure 12. Flowchart 99 Figure 13. Forest Plot 101 Figure
14. Frequency Polygon 103 Figure 15. Gantt Chart 107 Figure 16. Histogram
116 Figure 17. Isometric Graph 136 Figure 18. J-shaped Curve 137 Figure 19.
Left Skew Distribution 143 Figure 20. Logistic Curve 147 Figure 21. Normal
Distribution 172 Figure 22. Open Sequential Design 180 Figure 23. Poisson
Distribution 199 Figure 24. Right Skew Distribution 239 Figure 25. s-shaped
Curve 241 Figure 26. Scatter Diagram 243 Figure 27. Survival Curve 270
Figure 28. t Distribution 273 Figure 29. Uniform Distribution 294 Figure
30. Venn Diagram 299