Jingwu Zhang (ed.)

Immune Regulation and Immunotherapy in Autoimmune Disease

Herausgegeben:Zhang, Jingwu

• Gebundenes Buch

Produktbeschreibung

This volume will review the most recent advances in the understanding of cellular and molecular mechanisms for immune responses and immune regulation. Chapters in the first portion of this book will discuss the theoretical basis for current immunotherapies for autoimmune diseases. The second portion of the book will provide an updated review on the research behind the clinical trials/immunotherapies (e.g. T-cell vaccination, antibody therapy, etc.) in the areas of autoimmune diseases by the principal investigators of these studies. These chapters will discuss clinical and basic research as well as immunological data in the context of cellular and molecular mechanisms of the therapies. The book will finish with chapters by leaders in the field who will provide expert views on challenges and future directions.

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This volume reviews the most recent advances in the understanding of cellular and molecular mechanisms for immune responses and immune regulation. The books editor, Dr. Zhang, is well-known internationally, particularly in the field of multiple sclerosis and T-cell vaccination as a potential treatment of multiple sclerosis. He has much experience and expertise in both basic and clinical aspects of autoimmune disease.

Produktdetails

• Verlag: Springer / Springer US / Springer, Berlin
• Artikelnr. des Verlages: 11418580, 978-0-387-36002-7
• 2007
• Seitenzahl: 600
• Erscheinungstermin: 26. Januar 2007
• Englisch
• Abmessung: 241mm x 160mm x 41mm
• Gewicht: 1166g
• ISBN-13: 9780387360027
• ISBN-10: 0387360026
• Artikelnr.: 20947292

Inhaltsangabe

Immune Regulation and Autoimmune Disease.- Autoimmune Response and Immune Tolerance.- Priming Regulatory T Cells and Antigen-Specific Suppression of Autoimmune Disease.- Peripheral T Cell Regulation and Autoimmunity.- Anti-Ergotypic Regulation of the Immune Response.- How B Cells Contribute to Multiple Sclerosis Pathology.- Molecular Basis for Induction of Tolerance in Type I Diabetes.- Co-stimulation Regulation of Immune Tolerance and Autoimmunity.- Invariant NKT Cells and Immune Regulation in Multiple Sclerosis.- CD4+CD25+ Regulatory T Cells in Autoimmune Disease.- Immunopathogenesis of Multiple Sclerosis: Overview.- Viral Infection and Multiple Sclerosis.- Multiple Sclerosis Pathology During Early and Late Disease Phases: Pathogenic and Clinical Relevance.- CD8+ T Cells in Multiple Sclerosis.- Novel Immunotherapeutic Strategies and Emerging Treatments.- Review of Novel Immunotherapeutic Strategies for MS.- T Cell Vaccination in Autoimmune Disease.- Trivalent T Cell Receptor Peptide Vaccine for Treatment of Multiple Sclerosis Targets Predominant V Genes Widely Implicated in Autoimmune Diseases and Allergy.- Nonmyeloablative Stem Cell Transplantation for Multiple Sclerosis.- T Cell-Targeted Therapy for Rheumatoid Arthritis.- Estrogens in the Treatment of Multiple Sclerosis.- Immune Regeneration Through Hematopoietic Stem Cell Transplantation to Restore Tolerance in Autoimmune Disease.- Cell Transplantation of Peripherally Derived Adult Cells for Promoting Recovery from CNS Injury.- Multiple Sclerosis: Future Directions and Prospects.