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With implications that go to the core of what it means to be human,the issues raised by genetic manipulation-especially cloning-havesparked a passionate debate among governmental, religious, andscientific quarters, as well as the media and the general public.Keeping to the actual science rather than speculation is of theutmost importance for an enlightened approach to this weightydiscussion. In clear, lively prose, The Science and Ethics ofEngineering the Human Germ Line: Mendel's Maze provides anauthoritative treatment of the principles of science and bioethicsthat bear upon such technologies…mehr

Produktbeschreibung
With implications that go to the core of what it means to be human,the issues raised by genetic manipulation-especially cloning-havesparked a passionate debate among governmental, religious, andscientific quarters, as well as the media and the general public.Keeping to the actual science rather than speculation is of theutmost importance for an enlightened approach to this weightydiscussion. In clear, lively prose, The Science and Ethics ofEngineering the Human Germ Line: Mendel's Maze provides anauthoritative treatment of the principles of science and bioethicsthat bear upon such technologies as germ-line insertion andcloning. It offers a realistic assessment of possible applications,limitations, and new developments likely to arise in theseareas. Written by a top physician-investigator, this book progressesfrom the basics of building a living organism from inanimate partsthrough to recombinant DNA technology, assisted reproductivetechnologies, and gene transfer and germ-line engineering. Ethicalconsiderations are woven into this material throughout, while aspecial section covers the intellectual role played by varioussocial biases. As genetic and reproductive technologies spread from thelaboratory to the clinic-and society takes further notice-studentsand practitioners of biology and medicine, as well as theinterested general reader, will find The Science and Ethicsof Engineering the Human Germ Line: Mendel's Maze to be anessential and accessible guide to these important subjects.

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  • Produktdetails
  • Verlag: John Wiley & Sons
  • Seitenzahl: 304
  • Erscheinungstermin: 10.09.2003
  • Englisch
  • ISBN-13: 9780471478201
  • Artikelnr.: 37302105
Autorenporträt
Dr. Gordon graduated from Columbia University with a major in Biology in 1971. He obtained a Ph.D. Yale University in 1978, receiving an award for the best Ph.D. thesis in Biology that year. In 1980 Dr. Gordon graduated with honors from Yale University Medical School. In the two years following medical school Dr. Gordon, in collaboration with Frank H. Ruddle at Yale University, produced the first "transgenic" mouse, a mouse with genes from another species inserted into the germ line. Since then he has pioneered new techniques for assisting fertilization in human in vitro fertilization and has published many research papers, reviews and opinion papers on the science and ethics of gene transfer and related reproductive technologies. He is an internationally recognized authority in the area of germ line gene transfer.
Inhaltsangabe
Preface.
Acknowledgments.
PART I.
1. Setting the Table.
2. Building a Living Organism from Inanimate Parts.
3. Molecular Biology and Recombinant DNA Technology.
4. Transmitting the Genetic Information to Future Generations.
5. Developmental Biology.
6. Reproductive Biology and Assisted Reproductive Technologies.
7. Methods and Strategies for Gene Transfer and Engineering of the Germ Line.
PART II.
8. Introduction to the Ethics of Reproductive Genetic Technologies.
9. Future Developments and Applications of Genetic Engineering Technology.
10. What If? Ethical and Legal Aspects of Germ Line Genetic Manipulation.
A Brief Epilogue: Understanding Our Biases.
Index.
Rezensionen
"...will help us engage in a sensible and productive discussion to decide collectively the role genetic technologies should play in our future." ( The Quarterly Review of Biology , December 2004)
"Academic, hospital, and corporate health sciences libraries would welcome this title as an asset to their collections." ( E-STREAMS , July 2004)

"...an essential and accessible guide to these important subjects. Dr. Gordon and John-Wiley Corporation jointly deserve a pat in the back for producing a beneficial and eye-opening book." ( Annals of Biomedical Engineering , August 2004)

"...elucidates the background of genetic manipulation for the layman...recommended..." ( Choice , Vol. 41, No. 8, April 2004)

"...this book succeeds in demystifying many of the issues surrounding germline genetic manipulations..." ( Science Books & Films , April 2004)

"This powerful ethical message, combined with Gordon s scientific acumen, make for a simultaneously accessible and thoughtful book." ( Yale Journal of Biology and Medicine , July 2003)