Andreas Ziegler, Inke R. König

A Statistical Approach to Genetic Epidemiology (eBook, ePUB)

Concepts and Applications, with an e-learning platform

• Format: ePub

Produktbeschreibung

Diese zweite Auflage des sehr erfolgreichen Lehrbuchs der Statistik in der genetischen Epidemiologie wurde sorgfältig durchgesehen, aktualisiert und an vielen Stellen erweitert. Wie gewohnt mit vielen Aufgaben und Lösungen, dazu jetzt auch Farbabbildungen und auf Wunsch gekoppelt mit einem maßgeschneiderten E-Learning-Kurs.

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Produktdetails

• Verlag: Wiley-VCH Verlag GmbH & Co. KGaA
• Seitenzahl: 498
• Erscheinungstermin: 24. August 2011
• Englisch
• ISBN-13: 9783527633661
• Artikelnr.: 37351171

Autorenporträt

After studying statistics and mathematics at the University of Munich and obtaining his doctoral degree from the University of Dortmund, Andreas Ziegler received the Johann-Peter-Süßmilch-Medal of the German Association for Medical Informatics, Biometry and Epidemiology for his post-doctoral work on "Model Free Linkage Analysis of Quantitative Traits" in 1999. In 2004, he was one of the recipients of the Fritz-Linder-Forum-Award from the German Association for Surgery. Andreas Ziegler is head of the Institute for Medical Biometry and Statistics at the University Clinic Schleswig-Holstein in Lübeck, an acknowledged center of excellence for genetic epidemiological methods. Currently he is President of the German Region of the International Biometric Society. Inke R. König studied psychology at the universities of Marburg (Germany) as a scholar of the German National Academic Foundation and Dundee (Scotland) with a grant from the German Academic Exchange Service (DAAD). She has done research work at the Institute of Medical Biometry and Epidemiology in Marburg and since 2001 at the Institute of Medical Biometry and Statistics in Lübeck. In 2004, she became vice director of the latter and also received the Fritz-Linder-Forum-Award from the German Association for Surgery. Besides holding the certificate "Biometrics in Medicine", she has collected teaching experience since 1998 as a lecturer for biomathematics, behavioural genetics, clinical epidemiology, genetic epidemiology, and evidence-based medicine. Friedrich Pahlke is Dipl. Inf. at the Institute for Medical Biometry and Statistics at the University Clinic Schleswig-Holstein in Lübeck. He has created the e-learning course which is optionally available with the book.

Inhaltsangabe

INTRODUCTORY GENETICS

Molecular Genetics

Formal Genetics

Genetic Markers

Data Quality

LINKAGE ANALYSIS

Genetic Map Distances

Model Based Linkage Analysis

Model Free Linkage Analysis for Dichotomous Traits

Model Free Linkage Analysis for Quantitative Traits

ASSOCIATION ANALYSIS

Fundamental Concepts

Case-Control Association Analysis

Family-Based Association Analysis

Haplotypes in Association Analyses

Appendix: Algorithms Used in Linkage Analyses

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INTRODUCTORY GENETICS Molecular Genetics Formal Genetics Genetic Markers
Data Quality LINKAGE ANALYSIS AND FAMILY STUDIES Genetic Map Distances
Model Based Linkage Analysis Model Free Linkage Analysis for Binary Traits
Model Free Linkage Analysis for Quantitative Traits Family Studies not
Involving Genetic Markers ASSOCIATION ANALYSIS Fundamental Concepts of
Association Analyses Association Analysis with Unrelated Individuals Family
Based Association Analysis Haplotypes GWAs Appendix Solutions References