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The last systematic description of heme peroxidases was published in 1999 by Brian Dunford, from the University of Alberta in Canada. The book Heme per- idases covers discussion on three-dimensional structure, reaction mechanism, kinetics, and spectral properties of representative enzymes from bacterial, plant, fungal, and animal origin. Since 1999, vast information on basic but also applied aspects of heme peroxidases has been generated. We believe fusion of these two aspects will bene?t research of those dedicated to development of biocatalytic process. The aim of this book is to present…mehr

Produktbeschreibung
The last systematic description of heme peroxidases was published in 1999 by Brian Dunford, from the University of Alberta in Canada. The book Heme per- idases covers discussion on three-dimensional structure, reaction mechanism, kinetics, and spectral properties of representative enzymes from bacterial, plant, fungal, and animal origin. Since 1999, vast information on basic but also applied aspects of heme peroxidases has been generated. We believe fusion of these two aspects will bene?t research of those dedicated to development of biocatalytic process. The aim of this book is to present recent advances on basic aspects such as evolution, structure-function relation, and catalytic mechanism, as well as applied aspects, such as bioreactor and protein engineering, in order to provide the tools for rational design of enhanced biocatalysts and biocatalytic processes. The book does not include an exhaustive listing of references but rather a selected collection to enrich discussion and to allow envisioning future directions for research. This book is organized in three parts. In Part I, current knowledge of structure and mechanism of peroxidases is covered. From the molecular phylogeny, going through the in?uence of structural factors over oxidative ability to the molecular mechanism of catalysis, the authors intend to provide an understanding of per- idases at the molecular level. The understanding of the fundamental behavior of peroxidases will allow further adequation, design, and/or optimization of pero- dase-based catalysis to a particular process. In Part II, research on potential applications of peroxidases in several ?elds is presented and discussed.
Inhaltsangabe
1.-IntroductionMOLECULAR AND STRUCTURAL ASPECTS OF PEROXIDASES2.- Molecular phylogeny of heme peroxidases (Marcel Zámocký and Christian Obinger)3.- Structural and functional features of peroxidases with a potential as industrial biocatalysts (Francisco J. Ruiz-Dueñas and Angel T. Martínez)4.-Redox potential of heme peroxidases (Marcela Ayala)5.- Catalytic mechanisms of heme peroxidases (Paul R. Ortiz de Montellano)PROSPECTIVE USAGE OF PEROXIDASES IN INDUSTRY6.- Potential applications of peroxidases in the fine chemicals industry (Luigi Casella, Enrico Monzani and Stefania Nicolis)7.- Grafting of functional molecules: insights into peroxidase-derived materials (Gibson S. Nyanhongo, Endry Nugroho Prasetyo, Tukayi Kudanga and Georg Guebitz )8.- Applications and prospective of peroxidase biocatalysis in the environmental field (Cristina Torres-Duarte and Rafael Vazquez-Duhalt)CHALLENGES IN THE APPLICATION OF PEROXIDASES9.-Enzyme technology of peroxidases: immobilization, chemical and genetic modification (Adriana Longoria, Raunel Tinoco and Eduardo Torres).10.- Reactor engineering (Juan M. Lema, Carmen López, Gemma Eibes, Roberto Taboada-Puig, M. Teresa Moreira and Gumersindo Feijoo)11.- Deactivation of heme peroxidases by hydrogen peroxide: focus on Compound III (Brenda Valderrama)12.- Heterologous expression of peroxidases (Sandra de Weert and B. Christien Lokman)13.- A compendium of bio-physical-chemical properties of peroxidases (Humberto García-Arellano)