Human Reproductive and Prenatal Genetics

Herausgegeben:Leung, Peter C. K.; Qiao, Jie

• Broschiertes Buch

Produktbeschreibung

Human Reproductive and Prenatal Genetics presents the latest material from a detailed molecular, cellular and translational perspective. Considering its timeliness and potential international impact, this all-inclusive and authoritative work is ideal for researchers, students, and clinicians worldwide. Currently, there are no comprehensive books covering the field of human reproductive and prenatal genetics. As such, this book aims to be among the largest and most useful references available.

Named a Highly Commended book in the Basic and Clinical Sciences by the British Medical Association.

Features chapter contributions from leading international scientists and clinicians Provides in-depth coverage of key topics in human reproductive and prenatal genetics, including genetic controls, fertilization and implantation, in vitro culture of the human embryo for the study of post-implantation development, and more Identifies how researchers and clinicians can implement the latest genetic, epigenetic, and -omics based approaches

Produktdetails

• Verlag: Academic Press
• Artikelnr. des Verlages: 73038590
• Seitenzahl: 709
• Erscheinungstermin: 12. September 2018
• Englisch
• Abmessung: 392mm x 235mm x 37mm
• Gewicht: 1460g
• ISBN-13: 9780128135709
• ISBN-10: 0128135700
• Artikelnr.: 52410714

Inhaltsangabe

Part I. Reproductive Tract Development and Gametogenesis 1. Developmental Genetics of the Male Reproductive System 2. Genetics and genomics of early gonad development 3. Genetics of Meiotic Chromosome Dynamics and Fertility 4. Effects of Aging on Sperm Chromatin 5. In Vitro Spermatogenesis from Pluripotent Stem Cells 6. Developmental Genetics of the Female Reproductive Tract 7. The Molecular Genetics of Oogenesis 8. Epigenetic Control of Oocyte Development 9. RNA Binding Protein Networks and Translational Regulation in Oocytes 10. Translational Regulation of Gene Expression during Oogenesis and Pre-implantation Embryo Development 11. MicroRNAs in Gametes and Preimplantation Embryos: Clinical Implications

Part II. Embryo Implantation, Placenta Development and Pregnancy 12. Transcriptomics of the Human Endometrium and Embryo Implantation 13. Epigenetic Modifications in the Human Placenta 14. microRNAs in pregnancy: implications for basic research and clinical management 15. Genetics and Genomics of Preterm Birth 16. The Intergenerational Effects on Fetal Programming

Part III. Infertility and Assisted Reproductive Technology 17. Genetic Testing in Male Infertility 18. Genetics and Genomics of Endometriosis 19. Genetics and Genomics of Primary Ovarian Insufficiency 20. Genetics of Polycystic Ovary Syndrome 21. Genetics and Genomics of Recurrent Pregnancy Loss 22. Human Genetics and Assisted Reproduction in Endometriosis 23. Uterine Transplantation

Part IV. Preimplantation/Prenatal Genetic Diagnosis and Screening 24. Epidemiology and Genetics of Human Aneuploidy 25. Next Generation Sequencing for Gene Panels and Clinical Exomes 26. Chromosomal Microarrays and Exome Sequencing for Diagnosis of Fetal Abnormalities 27. Noninvasive Prenatal Testing for Genetic Diseases 28. Non-Invasive Prenatal Testing by Cell-Free DNA: Technology, Biology, Clinical Utility and Limitations 29. Prenatal diagnosis and treatment of genetic steroid disorders 30. Application of Gene-Editing Technologies in Embryos and Their Potential for Gene Therapy

Rezensionen

"Most books available in the literature are either eminently clinical or geared toward basic research science. This book is a unique attempt to combine both." --Doody