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DNA as the genetic material is a topic of intense interest in the 21st century with the familiar and iconic Watson-Crick double helix having a vital importance for its function. However, there are further complexities beyond the double helix, including supercoiling, knotting and catenation, that are less widely appreciated and understood but which are critical to its function. This book explains these topological aspects of DNA structure in a clear and approachable style that will be appreciated by both students and researchers interested in DNA structure and function.

Produktbeschreibung
DNA as the genetic material is a topic of intense interest in the 21st century with the familiar and iconic Watson-Crick double helix having a vital importance for its function. However, there are further complexities beyond the double helix, including supercoiling, knotting and catenation, that are less widely appreciated and understood but which are critical to its function. This book explains these topological aspects of DNA structure in a clear and approachable style that will be appreciated by both students and researchers interested in DNA structure and function.
Autorenporträt
Dr Andy Bates is at the School of Biological Sciences at the University of Liverpool, UK. Professor Tony Maxwell is Head of the Department of Biological Chemistry at the John Innes Centre, Norwich, UK.
Rezensionen
DNA Topology provides a solid basis for understanding the physical properties of DNA and its topology, and how this molecule actively participates in many cellular processes. This book is certainly aimed at specialists, whom it will not diappoint with its detailed treatment of the core subject matter. The Quarterly Review of Biology, Volume 81, March 2006.