Josip Lovric

Introducing Proteomics

From Concepts to Sample Separation, Mass Spectrometry and Data Analysis

• Gebundenes Buch

Produktbeschreibung

Contemporary, Broad Coverage covers every aspect of the rapidly changing field of proteomics from Coherent and Student friendly based on the highly successful course developed by the author at Manchester University. It tells students exactly what they need to know, without getting bogged down in too much detail.

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Introducing Proteomics gives a concise and coherent overview of every aspect of current proteomics technology, which is a rapidly developing field that is having a major impact within the life and medical sciences.

This student-friendly book, based on a successful course developed by the author, provides its readers with sufficient theoretical background to be able to plan, prepare, and analyze a proteomics study.

The text covers the following:
Separation Technologies
Analysis of Peptides/Proteins by Mass Spectrometry
Strategies in Proteomics

This contemporary text also includes numerous examples and explanations for why particular strategies are better than others for certain applications. In addition, Introducing Proteomics includes extensive references and a list of relevant proteomics information sources; essential for any student.

This no-nonsense approach to the subject tells students exactly what they need to know, leaving out unnecessary information. The student companion site enhances learning and provides answers to the end of chapter problems.

"I think this book will be a popular and valuable resource for students and newcomers to the field who would like to have an overview and initial understanding of what proteomics is about. The contents are well organized and address the major issues."
--Professor Walter Kolch, Director, Systems Biology Ireland & Conway Institute, University College Dublin

Companion Website
www.wiley.com/go/lovric

Produktdetails

• Verlag: Wiley & Sons / Wiley-Blackwell
• 1. Auflage
• Seitenzahl: 296
• Erscheinungstermin: 14. Februar 2011
• Englisch
• Abmessung: 249mm x 193mm x 23mm
• Gewicht: 747g
• ISBN-13: 9780470035238
• ISBN-10: 0470035234
• Artikelnr.: 32567673

Autorenporträt

Josip Lovric is the author of Introducing Proteomics: From Concepts to Sample Separation, Mass Spectrometry and Data Analysis, published by Wiley.

Inhaltsangabe

Preface. Acknowledgements. 1 Introduction. 1.1 What are the Tasks in
Proteomics? 1.2 Challenges in Proteomics. 1.3 Proteomics in Relation to
Other -omics and System Biology. 1.4 Some General Applications of
Proteomics. 1.5 Structure of the Book. References. 2 Separation and
Detection Technologies. 2.1 Introduction to Experimental Strategies in
Proteomics. 2.2 Gel-Based Separation. 2.3 Visualization and Analysis of
Proteins/Peptides in Gels. 2.4 Gel-Free Separation Technologies. 2.5.
Visualization of Proteins/Peptides from Hyphenated Methods. 2.6 Chips in
Proteomics Applications. References. 3 Analysis of Peptides/Proteins by
Mass Spectrometry. 3.1 Basic Principles of Mass Spectrometry for
Proteomics. 3.2 Ionization Methods for Small Amounts of Biomolecules. 3.3
Mass Aanalyzers and Mass Spectrometers. 3.4 Concluding Remarks on Mass
Analyzers for Proteomics. References. 4 Analysis and Interpretation of Mass
Spectrometric and Proteomic Data. 4.1 Introduction. 4.2 Analysis of MS
Data. 4.3 Analysis of MS/MS Data. 4.4 Quantification of LC MS and MS/MS
Data from Complex Samples. 4.5 Bioinformatic Approaches for Mass
Spectrometric Proteome Data Analysis. 5 Strategies in Proteomics. 5.1
Imaging Mass Spectrometry. 5.2 Qualitative Proteomics. 5.3 Differential and
Quantitative Proteomics. 5.4 Analysis of Posttranslational Modifications.
5.5 Interaction-Proteomics. 5.6 Proteomics as Part of Integrated
Approaches. References. Index.

Rezensionen

"He introduces undergraduate students to the general principles and methods of the field without delving very deeply into any of the details. Graduate students and researchers could also use the book to refresh their memory or catch up with recent developments." (Booknews, 1 June 2011)