J. G. Salway

Medical Biochemistry at a Glance (eBook, PDF)

• Format: PDF

Produktbeschreibung

Offering a concise, illustrated summary of biochemistry and its relevance to clinical medicine, Medical Biochemistry at a Glance is intended for students of medicine and the biomedical sciences such as nutrition, biochemistry, sports science, medical laboratory sciences, physiotherapy, pharmacy, physiology, pharmacology, genetics and veterinary science. It also provides a succinct review and reference for medical practitioners and biomedical scientists who need to quickly refresh their knowledge of medical biochemistry. The book is designed as a revision guide for students preparing for examinations and contains topics that have been identified as 'high-yield' facts for the United States Medical Licensing Examination (USMLE), Step 1. This third edition: * Has been thoroughly revised and updated and is now in full colour throughout * Is written by the author of the hugely successful Metabolism at a Glance (ISBN 9781405107167) * Features updated and improved clinical correlates * Expands its coverage with a new section on Molecular Biology * Includes a brand new companion website of self-assessment questions and answers at href="http://www.ataglanceseries.com/medicalbiochemistry">www.ataglanceseries.com/medicalbiochemistry

---

Dieser Download kann aus rechtlichen Gründen nur mit Rechnungsadresse in A, B, BG, CY, CZ, D, DK, EW, E, FIN, F, GR, HR, H, IRL, I, LT, L, LR, M, NL, PL, P, R, S, SLO, SK ausgeliefert werden.

Produktdetails

• Verlag: John Wiley & Sons
• Seitenzahl: 176
• Erscheinungstermin: 22. November 2011
• Englisch
• ISBN-13: 9781118292396
• Artikelnr.: 37348199

Autorenporträt

J. G. Salway is the author of Medical Biochemistry at a Glance, 3rd Edition, published by Wiley.

Inhaltsangabe

Preface to the third edition 7 Acknowledgements to the third edition 7
Figure key 8 SI/mass unit conversions 9 Part 1 Acids, bases and pH 1 Acids,
bases and hydrogen ions (protons) 10 2 Understanding pH 12 3 Production and
removal of protons into and from the blood 14 4 Metabolic alkalosis and
metabolic acidosis 16 5 Respiratory alkalosis and respiratory acidosis 18
Part 2 Structure of amino acids and proteins 6 Amino acids and the primary
structure of proteins 20 7 Secondary structure of proteins 22 8 Tertiary
and quaternary structure and collagen 24 Part 3 Formation of ATP: oxidation
and reduction reactions 9 Oxidation/reduction reactions, coenzymes and
prosthetic groups 26 10 Anaerobic production of ATP by substrate-level
phosphorylation, from phosphocreatine and by the adenylate kinase
(myokinase) reaction 28 11 Aerobic production of ATP 30 12 Biosynthesis of
ATP by oxidative phosphorylation I 32 13 Biosynthesis of ATP by oxidative
phosphorylation II 34 14 What happens when protons or electrons leak from
the respiratory chain? 36 15 Free radicals, reactive oxygen species and
oxidative damage 38 16 Aerobic oxidation of glucose to provide energy as
ATP 40 17 Anaerobic oxidation of glucose by glycolysis to form ATP and
lactate 42 18 Anaerobic glycolysis in red blood cells, 2,3-BPG (2,3-DPG)
and the Bohr effect 44 Part 4 Carbohydrates 19 Carbohydrates 46 20
Absorption of carbohydrates and metabolism of galactose 48 21 Fate of
glucose in liver: glycogenesis and lipogenesis 50 22 Fructose metabolism 52
23 Glucose homeostasis 54 24 Glucose-stimulated secretion of insulin from
²-cells 56 25 Regulation of glycogen metabolism 58 26 Glycogen breakdown
(glycogenolysis) and glycogen storage diseases 60 27 Insulin signal
transduction and diabetes mellitus 62 28 Diabetes mellitus 64 29 Alcohol
metabolism: hypoglycaemia, hyperlactataemia and steatosis 66 Part 5 Enzymes
and regulation of pathways 30 Enzymes: nomenclature, kinetics and
inhibitors 68 31 Regulation of enzyme activity 70 32 Regulation of
glycolysis and Krebs cycle 72 33 Oxidation of fatty acids to produce ATP in
muscle and ketone bodies in liver 74 34 Regulation of lipolysis,
²-oxidation, ketogenesis and gluconeogenesis 76 Part 6 Lipids and lipid
metabolism 35 Structure of lipids 78 36 Phospholipids I: phospholipids and
sphingolipids 80 37 Phospholipids II: micelles, liposomes, lipoproteins and
membranes 82 38 Metabolism of carbohydrate to cholesterol 84 39 VLDL and
LDL metabolism I: "forward" cholesterol transport 86 40 VLDL and LDL
metabolism II: endogenous triacylglycerol transport 88 41 HDL metabolism:
"reverse" cholesterol transport 90 42 Absorption and disposal of dietary
triacylglycerols and cholesterol by chylomicrons 92 43 Steroid hormones:
aldosterone, cortisol, androgens and oestrogens 94 Part 7 Metabolism of
amino acids and porphyrins 44 Urea cycle and overview of amino acid
catabolism 96 45 Non-essential and essential amino acids 98 46 Amino acid
metabolism: to energy as ATP; to glucose and ketone bodies 100 47 Amino
acid disorders: maple syrup urine disease, homocystinuria, cystinuria,
alkaptonuria and albinism 102 48 Phenylalanine and tyrosine metabolism in
health and disease 104 49 Products of tryptophan and histidine metabolism
106 50 Haem, bilirubin and porphyria 108 Part 8 Vitamins 51 Fat-soluble
vitamins I: vitamins A and D 110 52 Fat-soluble vitamins II: vitamins E and
K 112 53 Water-soluble vitamins I: thiamin, ribofl avin, niacin and
pantothenate 114 54 Water-soluble vitamins II: pyridoxal phosphate (B6) 116
55 Water-soluble vitamins III: folate and vitamin B12 118 56 Water-soluble
vitamins IV: biotin and vitamin C 120 Part 9 Molecular biology 57 The cell
cycle 122 58 Pyrimidine metabolism 124 59 Purine metabolism 126 60
Structure of DNA 128 61 The "central dogma" of molecular biology 130 62
Organisation of DNA in chromosomes 132 63 Replication of DNA (part 1) 134
64 Replication of DNA (part 2) 136 65 DNA damage and repair 138 66
Transcription of DNA to make messenger RNA (part 1) 140 67 Transcription of
DNA to make messenger RNA (part 2) 142 68 Transcription of DNA to make
transfer RNA 144 69 Transcription of DNA to make ribosomal RNA 146 70
Translation and protein synthesis 148 71 Comparison of DNA replication, DNA
transcription and protein synthesis in eukaryotes and prokaryotes 150 Part
10 Diagnostic clinical biochemistry 72 Diagnostic clinical biochemistry
(with Dr J. W. Wright FRCP, MRCPath) 152 Index 154

Rezensionen

I have taught biochemistry to medical students and to undergraduates and graduate students, at both Temple University School of Medicine and at Case Western Reserve University, since 1968, so that I have had a great deal of experience in the field and have a feel for what works well for medical students.
Medical Biochemistry at a Glance would be an excellent book for USMLE Step 1. In my experience, medical students (and pre-medical students) would greatly benefit from reading it in preparation for the exam.
This compares very well with Lippincott's Biochemistry - this has the right price and approach to compete with Lippincott for a less expensive and more accessible alternative to the larger text books that are out there.
I like the way it combines the metabolic pathways and principles in such a creative fashion, and the metabolism sections are among the best I have read and the easiest to understand. Metabolism is a very complicated subject and, in my experience, most teachers of the subject would really benefit from your text. (Richard W. Hanson, Case Western Reserve University School of Medicine)