Biochemical Pathways (eBook, PDF)

An Atlas of Biochemistry and Molecular Biology
Redaktion: Michal, Gerhard; Schomburg, Dietmar

• Format: PDF

Produktbeschreibung

The pathways and networks underlying biological function Now in its second edition, Biochemical Pathways continues to garner praise from students, instructors, and researchers for its clear, full-color illustrations of the pathways and networks that determine biological function. Biochemical Pathways examines the biochemistry of bacteria, plants, and animals. It offers a quick overview of the metabolic sequences in biochemical pathways, the chemistry and enzymology of conversions, the regulation of turnover, the expression of genes, the immunological interactions, and the metabolic background of health disorders. A standard set of conventions is used in all illustrations, enabling readers to easily gather information and compare the key elements of different biochemical pathways. For both quick and in-depth understanding, the book uses a combination of: * Illustrations integrating many different features of the reactions and their interrelationships * Tables listing the important system components and their function * Text supplementing and expanding on the illustrated facts In the second edition, the volume has been expanded by 50 percent. Text and figures have undergone a thorough revision and update, reflecting the tremendous progress in biochemical knowledge in recent years. A guide to the relevant biochemical databases facilitates access to the extensive documentation of scientific knowledge. Biochemical Pathways, Second Edition is recommended for all students and researchers in such fields as biochemistry, molecular biology, medicine, organic chemistry, and pharmacology. The book's illustrated pathways aids the reader in understanding the complex set of biochemical reactions that occur in biological systems. From the reviews: "... highly recommended for every scientist and student working in biochemistry." -Umwelt & Gesundheit 4/2012 (review in German language)

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Produktdetails

• Verlag: John Wiley & Sons
• Seitenzahl: 416
• Erscheinungstermin: 30. Januar 2013
• Englisch
• ISBN-13: 9781118656907
• Artikelnr.: 37755990

Autorenporträt

GERHARD MICHAL, PhD, has retired from research at Boehringer Mannheim GmbH (now Roche Diagnostics). He is internationally acclaimed for developing the "Biochemical Pathways" wall chart. The first edition, which was published some forty years ago, has been continuously updated and is used in many biochemistry laboratories around the world. DIETMAR SCHOMBURG, PhD, is a Full Professor and Head of the Department of Bioinformatics and Biochemistry at the Technische Universität Carolo-Wilhelmina in Braunschweig. His research interests include protein structure and function, structural biochemistry, bioinformatics, and enzyme information/metabolic networks. Dr. Schomburg has been widely praised for establishing BRENDA, the principal source of enzyme function and property data.

Inhaltsangabe

Preface to the Second Edition IX From the Preface to the First Edition X
Contributors XI 1 Introduction and General Aspects 1 Gerhard Michal and
Dietmar Schomburg 1.1 Organization of This Book 1 1.2 Carbohydrate
Chemistry and Structure 4 1.3 Amino Acid Chemistry and Structure 5 1.4
Lipid Chemistry and Structure 6 1.5 Physico-Chemical Aspects of Biochemical
Processess 8 2 The Cell and Its Contents 14 Gerhard Michal and Dietmar
Schomburg 2.1 Classification of Living Organisms 14 2.2 Structure of Cells
14 2.3 Protein Structure and Function 18 2.4 Enzymes 21 2.5 Regulation of
the Enzyme Activity 24 2.6 Nucleic Acid Structure 26 2.7 Genetic Code and
the Flow of Information 30 2.8 Polymeric Carbohydrates 31 2.9 Glycosylated
Proteins and Peptides 32 2.10 Lipid Aggregates and Membranes 35 3
Metabolism 37 3.1 Carbohydrate Metabolism and Citrate Cycle 37 Röbbe
Wünschiers 3.2 Amino Acids and Derivatives 58 Röbbe Wünschiers 3.3
Tetrapyrroles 82 Martina Jahn and Dieter Jahn 3.4 Lipids and Glycolipids 93
Röbbe Wünschiers 3.5 Steroids and Isoprenoids 107 Röbbe Wünschiers 3.6
Nucleotides and Nucleosides 124 Röbbe Wünschiers 3.7 Cofactors and Vitamins
133 Ida Schomburg 3.8 Nucleic Acid Metabolism in Bacteria 149 Susanne
Peifer and Elmar Heinzle 3.9 Nucleic Acid Metabolism in Eukarya 157 Helmut
Burtscher 3.10 Special Bacterial Metabolism and Biosynthesis of
Antimicrobials 164 Julia Garbe, Annika Steen and Max Schobert 3.11 Electron
Transfer Reactions and Oxidative Phosphorylation 183 Martina Jahn and
Dieter Jahn 3.12 Photosynthesis 188 Dieter Oesterhelt and Josef Wachtveitl
3.13 Plant Secondary Metabolism 193 Antje Chang 4 Protein Biosynthesis,
Modifications and Degradation 210 4.1 Protein Synthesis in Bacteria 210
Martina Jahn and Dieter Jahn 4.2 Protein Biosynthesis in Eukarya 219 Röbbe
Wünschiers 4.3 Cell Cycle in Eukarya 232 Stefan Ries 4.4 Posttranslational
Modification of Proteins 238 Röbbe Wünschiers 4.5 Protein Folding,
Transport / Targeting and Degradation 244 Petra Dersch 5 Viruses 261 Klaus
Klumpp 5.1 General Characteristics of Viruses 261 5.2 DNA Viruses 264 5.3
RNA Viruses 267 5.4 Retroviruses 268 6 Transport 272 6.1 Transport Through
Membranes 272 Wilhelm Just 6.2 Transport of Lipids in Plasma 279 Horst
Klima 6.3 Oxygen Transport by Hemoglobin 282 Gerhard Michal 7 Signal
Transduction and Cellular Communication 286 Gerhard Niederfellner 7.1
Intercellular Signal Transmission by Hormones 286 7.2 Nerve Conduction and
Synaptic Transmission 294 7.3 Principles of Intracellular Communication 296
7.4 Receptors Coupled to Heterotrimeric G-Proteins 299 7.5 Receptors Acting
Through Tyrosine Kinases 311 7.6 Programmed Cell Death (Apoptosis) 319 7.7
Receptors for Steroid and Thyroid Hormones, for Retinoids and Vitamin D 321
7.8 Cyclic GMP Dependent Pathways and Effects of Nitric Oxide (NO) 322 8
Immune System 325 Ernst Peter Rieber 8.1 Components of the Immune System
325 8.2 Generation of a Specific Immune Response 343 8.3 Pathologic Immune
responses 352 8.4 Adhesion of Leukocytes 354 Anton Haselbeck 9 Blood
Coagulation and Fibrinolysis 357 Peter Müller 9.1 Hemostasis 357 9.2
Initial Reactions 358 9.3 Coagulation Propagation and Control 359 9.4
Platelets (Thrombocytes) 362 9.5 Fibrinolysis 364 10 Biochemical Networks,
Bioinformatics and Systems Biology 366 Dietmar Schomburg 10.1 Systems
Biology and Networks 366 10.2 Modeling of Metabolic Fluxes 366 10.3
Biochemical Pathways Information Resources 366 Index 374

Rezensionen

"Michal and Schomburg (Technische Univ. Carolo-Whilhelmina, Germany) have reorganized, updated, and greatly expanded (over 100 pages of new content) this unique resource, keeping it an essential biochemical reference. Summing Up: Essential. Biochemistry collections, upper-division undergraduates through professionals." (Choice, 1 August 2013)

"Biochemical Pathways, Second Edition is recommended for all students and researchers in such fields as biochemistry, molecular biology, medicine, organic chemistry, and pharmacology. The book's illustrated pathways aids the reader in understanding the complex set of biochemical reactions that occur in biological systems." (Kingbook73.blogspot, 23 April 2013)

"This book, not too scary to read thanks to its compact size, served as a great reading for the incoming graduate students from the biology department and the chemical engineering department alike." (Biotechnology Journal, 1 January 2013)