Aminoacyl-tRNA Synthetases in Biology and Medicine (eBook, PDF)

Redaktion: Kim, Sunghoon

• Format: PDF

Produktbeschreibung

1 Synthetic and Editing Mechanisms of Aminoacyl-tRNA Synthetases

John J. Perona, Ita Gruic-Sovulj

2 Emergence and Evolution

Tammy J. Bullwinkle, Michael Ibba

3 Architecture and Metamorphosis

Min Guo, Xiang-Lei Yang

4 Protein-Protein Interactions and Multi-component Complexes of Aminoacyl-tRNA Synthetases

Jong Hyun Kim, Jung Min Han, Sunghoon Kim

5 Extracellular Activities of Aminoacyl-tRNA Synthetases: New Mediators for Cell-Cell Communication

Sung Hwa Son, Min Chul Park, and Sunghoon Kim

6. Non-catalytic Regulation of Gene Expression by Aminoacyl-tRNA Synthetases

Peng Yao, Kiran Poruri, Susan A. Martinis, Paul L. Fox

7 Amino-Acyl tRNA Synthetases Generate Dinucleotide Polyphosphates as Second Messengers: Functional Implications

Sagi Tshori, Ehud Razin, Hovav Nechushtan

8 Association of Aminoacyl-tRNA Synthetases with Cancer

Doyeun Kim, Nam Hoon Kwon, Sunghoon Kim

9 Pathogenic Implications of Human Mitochondrial Aminoacyl-tRNA Synthetases

Hagen Schwenzer, Joffrey Zoll, Catherine Florentz, Marie Sissler

10 Role of Aminoacyl-tRNA Synthetases in Infectious Diseases and Targets for Therapeutic Development

Varun Dewan, John Reader, Karin-Musier Forsyth

11 Flexizymes, Their Evolutionary History and Diverse Utilities

Toby Passioura, Hiroaki Suga

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Produktdetails

• Verlag: Springer-Verlag GmbH
• Seitenzahl: 350
• Erscheinungstermin: 28. April 2014
• Englisch
• ISBN-13: 9789401787017
• Artikelnr.: 43605191

Autorenporträt

1983-1986 Researcher, Genetic Eng. Center, KAIST, Korea 1991-1994 Post-doc, MIT, USA 1993-1994 Senior Scientist, Cubist Pharmaceuticals, USA 1994-2001 Associate Professor, Sung Kyun Kwan University, Korea 2001-present Professor, College of Pharmacy, Graduate Program in Bioinformatics , Genetic Engineering, Cancer Biology, Seoul National Univ. 1998-present Director, Center for Medicinal Protein Network and Systems Biology, Seoul National University 2008- Director, Information Center of Bio-pharmacological Network 2008- Director, Integrated Bioscience and Biotechnology Institute

Inhaltsangabe

Catalysis.- Emergence and Evolution.- Architecture.- Protein-protein Interactions and Multicomponent Complexes.- Interactions with RNAs.- Secretion and Circulation.- Regulatory Roles.- Neural Diseases.- Cancer.- Immune Diseases.- Pathologic Implications of Mitochondrial tRNA Synthetases .- Infectious Diseases.- Reprogramming of Genetic Code.- Novel functions of tRNAs.- Perspectives for Systems and Synthetic Bio-Medicine.