Tumor-Induced Immune Suppression
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This monograph, for the first time, presents a comprehensive overview of different mechanisms of immune dysfunction in cancer as well as therapeutic approaches to their correction. It discusses new mechanisms that have never been discussed in a monograph before.

Produktbeschreibung
This monograph, for the first time, presents a comprehensive overview of different mechanisms of immune dysfunction in cancer as well as therapeutic approaches to their correction. It discusses new mechanisms that have never been discussed in a monograph before.
  • Produktdetails
  • Verlag: Springer, Berlin
  • 2008
  • Seitenzahl: 312
  • Erscheinungstermin: 29. Oktober 2010
  • Englisch
  • Abmessung: 235mm x 155mm x 16mm
  • Gewicht: 475g
  • ISBN-13: 9781441924001
  • ISBN-10: 1441924000
  • Artikelnr.: 32215184
Inhaltsangabe
Immune-Suppressive Mechanisms and Cancer: Understanding the Implications, Paradoxes, and Burning Questions.- Mechanisms of Tumor-Associated T-Cell Tolerance.- Contribution of B7-H1/PD-1 Co-inhibitory Pathway to T-Cell Dysfunction in Cancer.- Regulatory T Cells in Cancer.- Cancer-Induced Signaling Defects in Antitumor T Cells.- Immunobiology of Dendritic Cells in Cancer.- Macrophages and Tumor Development.- Myeloid-Derived Suppressor Cells in Cancer.- Signaling Pathways in Antigen-Presenting Cells Involved in the Induction of Antigen-Specific T-Cell Tolerance.- Arginine Availability Regulates T-Cell Function in Cancer.- Protein-Glycan Interactions in the Regulation of Immune Cell Function in Cancer: Lessons from the Study of Galectins-1 and -3.- Role of Reactive Oxygen Species in T-Cell Defects in Cancer.- Tumor Stroma and the Antitumor Immune Response.
Rezensionen
From the reviews:

"The overall goal of this book is to describe what is currently known about the ways tumors circumvent destruction by the host's immune system. ... The book is targeted at researchers -- immunologists in general and, more specifically, tumor immunologists. It also provides a good source of information for graduate students and postdoctoral fellows. The editors of the book and the authors of the chapters are authorities in the areas they discuss. ... a useful addition to the field." (Marion C. Cohen, Doody's Review Service, August, 2008)