Jürgen Rettinger, Silvia Schwarz, Wolfgang Schwarz

Electrophysiology

Basics, Modern Approaches and Applications

• Gebundenes Buch

Produktbeschreibung

This textbook presents a broad overview of topics concerning cellular electrophysiology - covering topics ranging from bioelectric phenomena recognized as far back as ancient Egypt to popular topics on the dangers of electrosmog. Without sacrificing scientific precision, this clear and concise work presents on the one hand the different methods and applications, on the other hand the biophysical fundamentals of ion-channel and carrier proteins. Numerous and carefully selected illustrations and diagrams supplement the text, while questions at the end of each chapter allow readers to test their understanding. Each section also includes references to relevant original literature for further reading. The book offers a valuable resource for students of biology, chemistry and physics with a special interest in biophysics.

Produktdetails

• Verlag: Shaker-Verlag / Springer / Springer International Publishing / Springer, Berlin
• Artikelnr. des Verlages: 978-3-319-30011-5
• 1st ed. 2016
• Seitenzahl: 162
• Englisch
• Abmessung: 247mm x 169mm x 15mm
• Gewicht: 524g
• ISBN-13: 9783319300115
• ISBN-10: 3319300113
• Artikelnr.: 44432159

Autorenporträt

Dr. phil.nat. Jürgen RETTINGER
Product Manager
Multi Channel Systems MCS GmbH
Aspenhaustrasse 21
72770 Reutlingen, Germany

Jürgen Rettinger received his doctor degree in physics at Goethe-University in Frankfurt. in 1995. His focus as group leader at Max-Planck-Institute of Biophysics in Frankfurt was research of structure-function relationships of ligand-gated ion channels and teaching electrophysiology at Goethe-University Frankfurt, Shanghai Institutes of Biological Sciences and Fudan-University Shanghai. Since 2008 Jürgen Rettinger is working with Multi Channel Systems responsible as product manager for electrophysiology.

Silvia SCHWARZ
Research Scientist
Shanghai Key Laboratory for Acupuncture Mechanism and Acupoint Function
Fudan University
Guoshoujing Rd. 199
Shanghai 201203, China

Silvia Schwarz finished her university education in biology and chemistry at Albert-Ludwigs-University Freiburg in 1974. Thereafter, she was educated and worked as teacher in biology and chemistry until 2008. Since then she works as research associate at Shanghai Research Center for Acupuncture and Meridians (Shanghai Key Laboratory of Acupuncture Mechanism and Acupoint Function, Fudan Univ.). Silvia Schwarzâs main research focus is on antiviral effects of Chinese herbal drugs applying electrophysiological methods.

Prof. Dr. rer.nat. Wolfgang SCHWARZ
Professor for Physics
Institut für Biophysik, Goethe-Universität Frankfurt
Max-von-Laue-Str. 1,
60438 Frankfurt a.M., Germany
Shanghai Key Laboratory for Acupuncture Mechanism and Acupoint Function
Fudan University
Guoshoujing Rd. 199
Shanghai 201203, China

Wolfgang Schwarz received his doctor degree in physics at University of Saarland in 1975. Thereafter, he spent two years as postdoc at University of Washington Seattle working on characteristics of ion channels. In 1981 he habilitated in physiology at University of Saarland and received a position as head of a Cell Physiology Laboratory at Max-Planck-Institute of Biophysics Frankfurt. Wolfgang Schwarzâs main focus turned to structure-function and regulation of carrier transporters and teaching electrophysiology as professor for physics at Goethe-University Frankfurt, Shanghai Institutes of Biological Sciences and Fudan-University Shanghai. Since 2004 Wolfgang Schwarz is head of the Cell Electrophysiology Laboratory of Shanghai Research Center for Acupuncture and Meridian (Shanghai Key Laboratory of Acupuncture Mechanism and Acupoint Function, Fudan Univ.) and concurrent professor at Fudan University.

Inhaltsangabe

Chapter 11 Introduction1.1 INTRODUCTORY OVERVIEW1.2 HISTORY OF ELECTROPHYSIOLOGY
Chapter 22 Basics: Theory2.1 ELECTRICAL CHARACTERISTICS OF BIOLOGICAL MEMBRANES2.2 ION DISTRIBUTION AT BIOLOGICAL MEMBRANES2.3 DONNAN DISTRIBUTION AND NERNST EQUATION2.4 GOLDMAN-HODGKIN-KATZ EQUATION
Chapter 33. Basics: Methods3.1 RECORDING ELECTRICAL SIGNALS FROM BODY SURFACE3.2 THE EXAMPLE (ECG)3.3 RECORDING ELECTRICAL SIGNALS FROM TISSUE3.4 RECORDING ELECTRICAL SIGNALS FROM SINGLE CELLS3.5 APPLICATION OF THE VOLTAGE-CLAMP TECHNIQUE3.6 THE PATCH-CLAMP TECHNIQUE
Chapter 44 Automated Electrophysiology4.1 AUTOMATED TWO-ELECTRODE VOLTAGE CLAMP4.2 AUTOMATED PATCH CLAMP
Chapter 55 Ion-selective Channels5.1 GENERAL CHARACTERISTICS OF ION CHANNELS5.2 SPECIFIC ION CHANNELS
Chapter 66 Theory of Excitability6.1 THE HODGKIN-HUXLEY DESCRIPTION OF EXCITATION6.2 CONTINUOUS AND SALTATORY CONDUCTION OF ACTION POTENTIALS6.3 GENERATION AND TRANSMISSION OF ACTION POTENTIALS6.4 SUMMARY OF THE DIFFERENT TYPES OF POTENTIALS6.5 ACTION POTENTIAL IN NON-NERVE CELLS
Chapter 77 Carrier-mediated Transport7.1 GENERAL CHARACTERISTICS OF CARRIERS7.2 CARRIERS ARE LIKE CHANNELS WITH ALTERNATING GATES
Chapter 88 Examples of Application of Electrophysiology8.1 STRUCTURE-FUNCTION RELATIONSHIPS OF CARRIER PROTEINS8.2 STRUCTURE-FUNCTION RELATIONSHIPS OF ION CHANNELS8.3 VIRAL ION CHANNELS
AppendixA1. THE GRAPH THEORYA2. INFLUENCE OF EXTERNAL ELECTRICAL AND MAGNETIC FIELDS A2.1. MAGNETOSTATIC FIELDSA3. A LABORATORY COURSE:
Important Physical UnitsList of Symbols and AbbreviationsIndex