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This book provides a basic, practical understanding of anesthesia for the commonly used rodent species: rats, mice, guinea pigs, hamsters, and gerbils. The main foci are to understand the basic anesthetic machine and commonly used breathing circuits, anesthetic agent pharmacology, pain management, pre-, peri- and post-operative care, and other select, special techniques. The book is informative, user-friendly, and easily understood. It focuses on essential matters to achieve safe and sound anesthesia and on topics relevant to research study and interest.