Analgesic and Antiinflammatory activity of Spinacia oleracea Linn
Versandkostenfrei!
Versandfertig in 6-10 Tagen
33,99 €
inkl. MwSt.
PAYBACK Punkte
17 °P sammeln!
The purpose of the present investigation was to evaluate the possible Analgesic, Anti-Inflammatory activities of Spinacia olearacea Linn.The ethanolic (80%) extract elicited a highly significant (p0.001) analgesic activity on hot plate method, acetic acid induced writhing test.In the hot plate method, the extract increased the reaction time of heat sensation to 73.3 %and 92.8% at the doses of 250 and 500 mg/kg BW respectively while that of the standard drug was 97.3% at the 3rd hour of study. In acetic acid induced writhing test, the percent inhibition of writhing response by the extract was 3...
The purpose of the present investigation was to evaluate the possible Analgesic, Anti-Inflammatory activities of Spinacia olearacea Linn.The ethanolic (80%) extract elicited a highly significant (p0.001) analgesic activity on hot plate method, acetic acid induced writhing test.In the hot plate method, the extract increased the reaction time of heat sensation to 73.3 %and 92.8% at the doses of 250 and 500 mg/kg BW respectively while that of the standard drug was 97.3% at the 3rd hour of study. In acetic acid induced writhing test, the percent inhibition of writhing response by the extract was 39.23% and 64.62% at 250 and 500 mg/kg doses respectively (p0.001) while the standard Ketorolac inhibition was 66%.The oral administration of the extract significantly (p0.001) inhibited inflammatory response induced by carrageenan in a dose dependent fashion. The most prominent inhibition of 80% (250 mg/kg) and 94% (500 mg/kg) were observed at the 2nd hour of study, while the standard drug Ketorolac showed 90% inhibition. All these studies suggest that Ethanolic (80%) extract of leaf of Spinacia olearacea L. has significant analgesic and anti-inflammatory effect in a dose dependent manner.
Andere Kunden interessierten sich für
