Synthetic Studies on N-aryl-gamma-lactams
Selective Functional Group Transformations and Development of Synthetic Routes to N-aryl-pyrroles and Pyrroloquinolines
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Due to growing number of bacterial strains acquiring resistance to the current arsenal of chemotherapeutic drugs, the search for novel anti bacterial agents continue to be a major area of research in many fronts.During the last decade,various groups have directed their efforts to synthesize various bioactive gamma-lactams. Modification of lactam ring has been playing a vital role in determining the bio-activities of these derivatives and so exploration of a novel methodology in a simple way is a pivotal focal point of research activity in bioorganic chemistry. Progress in the art of organic sy...
Due to growing number of bacterial strains acquiring resistance to the current arsenal of chemotherapeutic drugs, the search for novel anti bacterial agents continue to be a major area of research in many fronts.During the last decade,various groups have directed their efforts to synthesize various bioactive gamma-lactams. Modification of lactam ring has been playing a vital role in determining the bio-activities of these derivatives and so exploration of a novel methodology in a simple way is a pivotal focal point of research activity in bioorganic chemistry. Progress in the art of organic synthesis in the last decades has been achieved by marked advances in chemo-,regio-and stereoselective functional group transformations by using classical and newly developed reagents. The book entitled "Synthetic Studies on N-aryl- gamma-lactams" is an embodiment of research aimed at developing simple methodologies for selective functional group transformations of N-aryl- gamma-lactams and aneffort towards the development of new synthetic strategies for conversion of N-aryl- gamma-lactams to substituted pyrrole and pyrroloquinoline derivatives.
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