Kinetic and Mechanistic Study of Bromination of Benzofuran Scaffolds

Kinetic and Mechanistic Study of Bromination of Benzofuran Scaffolds

Kinetics of Bromination of substituted acetyl benzofurans with QATBs and Synthesis of its ¿-bromoderivatives

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It is difficult to imagine the synthesis without organobromides. It has been widely used as reactive intermediates and as a versatile synthons in various organic syntheses. -Bromination of carbonyl compound is an important reaction in organic synthesis; as the resulting -bromo-ketones are used in the synthesis of variety of bioactive molecules. Clinically, physiologically important and widely used benzofuran derivatives can be obtained from -bromo carbonyl compounds. In recent past, organic Quaternary Ammonium tribromide (QATBs) have been reported to be crystalline, highly efficient, selective...