Liquid filled capsule dosage form

Liquid filled capsule dosage form

Design and development of Liquid filled capsules

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Until the advent of soft gelatin capsules there were no significant changes in capsule manufacturing. Then it became a trend for liquid substances to be filled into soft gelatin capsules and hard gelatin capsules were allocated for dry fill only. However, the filling of molten or thixotropic liquids into hard gelatin capsules is more advantageous when compared to liquid filled soft capsules and may be employed to overcome a number of problems which are frequently associated with the development and manufacture of conventional capsules. This book highlights the basis for development of liquid f...