Biochemical and Hormones Study on Diabetic Nephrotic Patients
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Background: Diabetes mellitus is a growing epidemic and is the most common cause of chronic kidney disease (CKD) and kidney failure. Diabetic nephropathy affects approximately 20-40% of individuals who have diabetes.Diabetic nephropathy can be detected by the measurement of urine albumin or serum creatinine. Visceral adipose tissue-derived serine proteinase inhibitor (vaspin) was identified in the visceral adipose tissue of OLETF (Otsuka Long-Evans Tokushim a Fatty) rats, an animal model of obesity and type 2 diabetes mellitus (T2DM). Material and methods: In this study conducted on 70 individ...
Background: Diabetes mellitus is a growing epidemic and is the most common cause of chronic kidney disease (CKD) and kidney failure. Diabetic nephropathy affects approximately 20-40% of individuals who have diabetes.Diabetic nephropathy can be detected by the measurement of urine albumin or serum creatinine. Visceral adipose tissue-derived serine proteinase inhibitor (vaspin) was identified in the visceral adipose tissue of OLETF (Otsuka Long-Evans Tokushim a Fatty) rats, an animal model of obesity and type 2 diabetes mellitus (T2DM). Material and methods: In this study conducted on 70 individuals in the age group of 35-70 years, from Kirkuk General Hospital. Study group consists of 40 individuals with diabetic nephropathy and 30 ages and sex matched healthy individuals (control). Results: Serum vaspin of diabetic nephropathy patients showed a high significant relationship (p0.0001). As compared with the controls. There is high significant decrease (p0.001) in the serum levels ofT4 and T3. There is high significant increase (p0.001) in the serum levels of TSH as compared with the controls.
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