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Produktbild: TRP Channels in Drug Discovery

TRP Channels in Drug Discovery Volume I

Aus der Reihe Methods in Pharmacology and Toxicology

175,99 €

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Beschreibung

Details

Einband

Taschenbuch

Erscheinungsdatum

23.08.2016

Herausgeber

Arpad Szallasi + weitere

Verlag

Humana Press

Seitenzahl

446

Maße (L/B/H)

25,4/17,8/2,5 cm

Gewicht

868 g

Auflage

Softcover reprint of the original 1st ed. 2012

Sprache

Englisch

ISBN

978-1-4939-6281-5

Beschreibung

Details

Einband

Taschenbuch

Erscheinungsdatum

23.08.2016

Herausgeber

Verlag

Humana Press

Seitenzahl

446

Maße (L/B/H)

25,4/17,8/2,5 cm

Gewicht

868 g

Auflage

Softcover reprint of the original 1st ed. 2012

Sprache

Englisch

ISBN

978-1-4939-6281-5

Herstelleradresse

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  • Produktbild: TRP Channels in Drug Discovery
  • Part I: Introduction 1. Introduction to TRPs: A Quest for Novel Drug Targets            Bernd Nilius 2. TRP-Mediated Cytoskeletal Reorganization: Implications for Disease and Drug Development            Chandan Goswami Part II: TRP Channels, from A1 to V4 3. TRPA1 in Drug Discovery            Jun Chen, Steve McGaraughty, and Philip R. Kym 4. Canonical Transient Receptor Potential Channel (TRPC) Expression, Regulation, and Function in Vascular and Airway Diseases            Brij B. Singh, Christina M. Pabelick, and Y.S. Prakash 5. TRPM2 Function and Potential as a Drug Target            Barbara A. Miller 6. The Ca2+-Activated Monovalent Cation Selective Channels TRPM4 and TRPM5            Colsoul Barbara, Kecskes Miklos, Philippaert Koenraad, Menigoz Aurelie, and Vennekens Rudi 7. The Emerging Role of TRPM7 in the Regulation of Magnesium Homeostasis            Vladimir Chubanov, Jonathan T. Eggenschwiler, Thomas Gudermann, and Alexey G. Ryazanov 8. TRPM8 Channels as Potential Therapeutic Targets for Pain, Analgesia, and Thermoregulation            David D. McKemy 9. TRPML Channels in Function, Disease, and Prospective Therapies            David A. Zeevi 10. The TRPP Signalling Module: TRPP2/Polycystin 1 and TRPP2/PKD1L1            Alexis Hofherr 11. TRPV1 as a Polymodal Sensor: Potential to Discover TRPV1 Antagonists Selective for Specific Activating Modalities            Olivier Radresa, Stephen Zicha, William Brown, and Jennifer M.A. Laird 12. Nociceptive and Non-Nociceptive Roles of TRPV3 and Its “Druggability”            Sungjae Yoo and Sun Wook Hwang 13. TRPV4 and Drug Discovery            Fabien Vincent and Matthew A.J.  Duncton Part III: TRPs and Airways 14. TRP Expression and Function in the Lung Airways            Alexander Dietrich and Thomas Gudermann 15. Hypoxia-Dependent TRP Channel Function in Pulmonary Arterial Smooth Muscle Cells            Beate Fuchs, Hermann Kalwa, Norbert Weissmann, Thomas Gudermann, and Alexander Dietrich 16. Endotoxin-Induced Airway Inflammation and Asthma Models            Zsuzsanna Helyes and Zsófia Hajna 17. Enhanced Cough, Animal Models            Raffaele Gatti, Pamela Pedretti, Romina Nassini, and Marcello Trevisani 18. Capsaicin Inhalation Test in Man            Eva Millqvist Part IV: TRPs and the Genitourinary (GU) Tract 19. TRP Channels in the Genitourinary (GU) Tract            Ana Charrua and Francisco Cruz 20. Animal Models of Cystitis            Célia D. Cruz and António Avelino 21. Overactive Bladder Models            Roberto Soler, Lysanne Campeau, Claudius Füllhase, and Karl-Erik Andersson            Alexis Hofherr 11. TRPV1 as a Polymodal Sensor: Potential to Discover TRPV1 Antagonists Selective for Specific Activating Modalities            Olivier Radresa, Stephen Zicha, William Brown, and Jennifer M.A. Laird 12. Nociceptive and Non-Nociceptive Roles of TRPV3 and Its “Druggability”            Sungjae Yoo and Sun Wook Hwang 13. TRPV4 and Drug Discovery            Fabien Vincent and Matthew A.J.  Duncton Part III: TRPs and Airways 14. TRP Expression and Function in the Lung Airways            Alexander Dietrich and Thomas Gudermann 15. Hypoxia-Dependent TRP Channel Function in Pulmonary Arterial Smooth Muscle Cells            Beate Fuchs, Hermann Kalwa, Norbert Weissmann, Thomas Gudermann, and Alexander Dietrich 16. Endotoxin-Induced Airway Inflammation and Asthma Models            Zsuzsanna Helyes and Zsófia Hajna 17. Enhanced Cough, Animal Models            Raffaele Gatti, Pamela Pedretti, Romina Nassini, and Marcello Trevisani 18. Capsaicin Inhalation Test in Man            Eva Millqvist Part IV: TRPs and the Genitourinary (GU) Tract 19. TRP Channels in the Genitourinary (GU) Tract            Ana Charrua and Francisco Cruz 20. Animal Models of Cystitis            Célia D. Cruz and António Avelino 21. Overactive Bladder Models            Roberto Soler, Lysanne Campeau, Claudius Füllhase, and Karl-Erik Andersson            Olivier Radresa, Stephen Zicha, William Brown, and Jennifer M.A. Laird 12. Nociceptive and Non-Nociceptive Roles of TRPV3 and Its “Druggability”            Sungjae Yoo and Sun Wook Hwang 13. TRPV4 and Drug Discovery            Fabien Vincent and Matthew A.J.  Duncton Part III: TRPs and Airways 14. TRP Expression and Function in the Lung Airways            Alexander Dietrich and Thomas Gudermann 15. Hypoxia-Dependent TRP Channel Function in Pulmonary Arterial Smooth Muscle Cells            Beate Fuchs, Hermann Kalwa, Norbert Weissmann, Thomas Gudermann, and Alexander Dietrich 16. Endotoxin-Induced Airway Inflammation and Asthma Models            Zsuzsanna Helyes and Zsófia Hajna 17. Enhanced Cough, Animal Models            Raffaele Gatti, Pamela Pedretti, Romina Nassini, and Marcello Trevisani 18. Capsaicin Inhalation Test in Man            Eva Millqvist Part IV: TRPs and the Genitourinary (GU) Tract 19. TRP Channels in the Genitourinary (GU) Tract            Ana Charrua and Francisco Cruz 20. Animal Models of Cystitis            Célia D. Cruz and António Avelino 21. Overactive Bladder Models            Roberto Soler, Lysanne Campeau, Claudius Füllhase, and Karl-Erik Andersson            Sungjae Yoo and Sun Wook Hwang 13. TRPV4 and Drug Discovery            Fabien Vincent and Matthew A.J.  Duncton Part III: TRPs and Airways 14. TRP Expression and Function in the Lung Airways            Alexander Dietrich and Thomas Gudermann 15. Hypoxia-Dependent TRP Channel Function in Pulmonary Arterial Smooth Muscle Cells            Beate Fuchs, Hermann Kalwa, Norbert Weissmann, Thomas Gudermann, and Alexander Dietrich 16. Endotoxin-Induced Airway Inflammation and Asthma Models            Zsuzsanna Helyes and Zsófia Hajna 17. Enhanced Cough, Animal Models            Raffaele Gatti, Pamela Pedretti, Romina Nassini, and Marcello Trevisani 18. Capsaicin Inhalation Test in Man            Eva Millqvist Part IV: TRPs and the Genitourinary (GU) Tract 19. TRP Channels in the Genitourinary (GU) Tract            Ana Charrua and Francisco Cruz 20. Animal Models of Cystitis            Célia D. Cruz and António Avelino 21. Overactive Bladder Models            Roberto Soler, Lysanne Campeau, Claudius Füllhase, and Karl-Erik Andersson            Fabien Vincent and Matthew A.J.  Duncton Part III: TRPs and Airways 14. TRP Expression and Function in the Lung Airways            Alexander Dietrich and Thomas Gudermann 15. Hypoxia-Dependent TRP Channel Function in Pulmonary Arterial Smooth Muscle Cells            Beate Fuchs, Hermann Kalwa, Norbert Weissmann, Thomas Gudermann, and Alexander Dietrich 16. Endotoxin-Induced Airway Inflammation and Asthma Models            Zsuzsanna Helyes and Zsófia Hajna 17. Enhanced Cough, Animal Models            Raffaele Gatti, Pamela Pedretti, Romina Nassini, and Marcello Trevisani 18. Capsaicin Inhalation Test in Man            Eva Millqvist Part IV: TRPs and the Genitourinary (GU) Tract 19. TRP Channels in the Genitourinary (GU) Tract            Ana Charrua and Francisco Cruz 20. Animal Models of Cystitis            Célia D. Cruz and António Avelino 21. Overactive Bladder Models            Roberto Soler, Lysanne Campeau, Claudius Füllhase, and Karl-Erik Andersson            Raffaele Gatti, Pamela Pedretti, Romina Nassini, and Marcello Trevisani 18. Capsaicin Inhalation Test in Man            Eva Millqvist Part IV: TRPs and the Genitourinary (GU) Tract 19. TRP Channels in the Genitourinary (GU) Tract            Ana Charrua and Francisco Cruz 20. Animal Models of Cystitis            Célia D. Cruz and António Avelino 21. Overactive Bladder Models            Roberto Soler, Lysanne Campeau, Claudius Füllhase, and Karl-Erik Andersson            Eva Millqvist Part IV: TRPs and the Genitourinary (GU) Tract 19. TRP Channels in the Genitourinary (GU) Tract            Ana Charrua and Francisco Cruz 20. Animal Models of Cystitis            Célia D. Cruz and António Avelino 21. Overactive Bladder Models            Roberto Soler, Lysanne Campeau, Claudius Füllhase, and Karl-Erik Andersson 19. TRP Channels in the Genitourinary (GU) Tract            Ana Charrua and Francisco Cruz 20. Animal Models of Cystitis            Célia D. Cruz and António Avelino 21. Overactive Bladder Models            Roberto Soler, Lysanne Campeau, Claudius Füllhase, and Karl-Erik Andersson            Ana Charrua and Francisco Cruz 20. Animal Models of Cystitis            Célia D. Cruz and António Avelino 21. Overactive Bladder Models            Roberto Soler, Lysanne Campeau, Claudius Füllhase, and Karl-Erik Andersson            Roberto Soler, Lysanne Campeau, Claudius Füllhase, and Karl-Erik Andersson