Reginald Dean / Edward J. Bilsky / S. Stevens Negus (ed.)

Gebundenes Buch

Opiate Receptors and Antagonists

From Bench to Clinic

Herausgegeben: Dean, Reginald; Bilsky, Edward J.; Negus, S. Stevens

Beschreibung

The evolution in our understanding of opioid receptors and their subtypes is in- mately linked to the development of new pharmacological treatments for diseases/ disorders as diverse as addiction, self-injurious behavior, pain, cancer, infl- mation, eating disorders, traumatic injury, pruritis, and movement disorders. These potential treatments involve both novel chemical entities and classic opioid antagonists with improved drug delivery systems. The contributions contained in Opioid Receptors and Antagonists: From Bench to Clinic represent the efforts from some of the leading international scientists and clinicians making use of the l- est information emerging from the study of the opioid receptor system. Given the number of researchers currently active in this and related fields of study, it would be inappropriate to suggest that the entire range of activities is fully reflected in this single volume. Instead, a variety of experimental and clinical approaches involving the fields of neuroscience, molecular biology, biochemistry, anatomy, pharmacology, psychology, and psychiatry have been chosen to illustrate rapidly developing experimental and therapeutic areas.

Produktdetails

• Contemporary Neuroscience
• Verlag: Humana / Humana Press / Springer, Berlin
• Artikelnr. des Verlages: 12015887, 978-1-58829-881-2
• 2009
• Seitenzahl: 784
• Erscheinungstermin: 9. März 2009
• Englisch
• Abmessung: 241mm x 160mm x 48mm
• Gewicht: 1270g
• ISBN-13: 9781588298812
• ISBN-10: 1588298817
• Artikelnr.: 22743240

Rezensionen

From the reviews:

"The authors do an excellent job of providing insight into the background of the many factors related to opioid receptor antagonists. ... Overall, this work is a well written and interesting text and would be a very useful addition to the personal libraries of those medicinal chemists with a research interest in the modulation of the opioid receptor system." (Thomas E. Prisinzano, Journal of Medicinal Chemistry, Vol. 53 (2), March, 2010)

"This book is focused on the therapeutic uses of opioid antagonists ranging from classical opioid antagonists to novel chemical entities. In any therapeutic field examined, the aim of book as outlined by the title-'From Bench to Clinic'-is achieved. ... The clinical applications of opioid antagonists are extensively discussed in almost all chapters of this book ... . In conclusion, this book gives an interesting analysis of the different fields of knowledge and research concerning therapeutic uses of opioid antagonists in recent years." (Agostino Marrazzo, ChemBioChem, Vol. 5, 2010)