This paper is a study of legal and practical issues of regulation of monopolistic activities in the Republic of Kazakhstan. Monopolistic activities limited by the legislation include - anticompetitive agreements, concerted actions and abuse of dominant position. In practice, companies in case of ignoring the requirements of antimonopoly legislation norms can be brought to criminal and administrative responsibility with payment of negotiable fines. The work will be of interest to students of higher educational institutions, scholars and lawyers practicing in the field of competition law, and foreign investors.