Green chemistry synthesis of selected aza heterocycles used in drugs
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The present work aimed to study the selected organic reaction i.e. synthesis of 1,4-dihydro-2,3-quinoxalinedione, 2,3-diphenyl quinoxaline and 4-(4-Hydroxyphenyl)-6-methyl-2-oxo-1,2,3,4-tetrahydropyrimidine-5-carboxylic acid ethyl ester under some alternative green techniques such as microwave irradiation, ultrasound, grindstone and application of eco-friendly solvent like water and ethanol. The aim included investigation of the effect of techniques mentioned above on reaction time as well as improvement in yield in comparison to conventional methods. The products obtained were also characteri...
The present work aimed to study the selected organic reaction i.e. synthesis of 1,4-dihydro-2,3-quinoxalinedione, 2,3-diphenyl quinoxaline and 4-(4-Hydroxyphenyl)-6-methyl-2-oxo-1,2,3,4-tetrahydropyrimidine-5-carboxylic acid ethyl ester under some alternative green techniques such as microwave irradiation, ultrasound, grindstone and application of eco-friendly solvent like water and ethanol. The aim included investigation of the effect of techniques mentioned above on reaction time as well as improvement in yield in comparison to conventional methods. The products obtained were also characterised.
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