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Produktbild: ATM Kinase
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ATM Kinase Methods and Protocols

Aus der Reihe Methods in Molecular Biology
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138,99 € UVP 160,49 €

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Beschreibung

Produktdetails

Einband

Taschenbuch

Erscheinungsdatum

20.07.2018

Abbildungen

XIV, 93 illus., 69 illus. in color., schwarz-weiss Illustrationen, farbige Illustrationen

Herausgeber

Sergei V. Kozlov

Verlag

Springer Us

Seitenzahl

437

Maße (L/B/H)

25,4/17,8/2,5 cm

Gewicht

854 g

Auflage

Softcover reprint of the original 1st ed. 2017

Sprache

Englisch

ISBN

978-1-4939-8350-6

Beschreibung

Produktdetails

Einband

Taschenbuch

Erscheinungsdatum

20.07.2018

Abbildungen

XIV, 93 illus., 69 illus. in color., schwarz-weiss Illustrationen, farbige Illustrationen

Herausgeber

Sergei V. Kozlov

Verlag

Springer Us

Seitenzahl

437

Maße (L/B/H)

25,4/17,8/2,5 cm

Gewicht

854 g

Auflage

Softcover reprint of the original 1st ed. 2017

Sprache

Englisch

ISBN

978-1-4939-8350-6

Herstelleradresse

Libri GmbH
Europaallee 1
36244 Bad Hersfeld
DE

Email: gpsr@libri.de

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  • Produktbild: ATM Kinase
  • 1. Assaying Radiosensitivity of Ataxia-Telangiectasia

                Hailiang Hu, Shareef Nahas, and Richard A. Gatti

     

    2. Assaying for Radioresistant DNA Synthesis, the Hallmark Feature of the Intra-S-Phase Checkpoint Using a DNA Fiber Fluorography-Based Methodology

                Amanda W. Kijas and Martin F. Lavin

     

    3. ATM Gene Mutation Detection Techniques and Functional Analysis

                Guillaume Rieunier, Catherine Dubois D’Enghien, Alice Fievet, Dorine Bellanger, Dominique Stoppa-Lyonnet, and Marc-Henri Stern

     

    4. An HTRF® Assay for the Protein Kinase ATM

                Phillip Adams, Jonathan Clark, Simon Hawdon, Jennifer Hill, and Andrew Plater

     

    5. ATM Kinase Inhibitors: HTS Cellular Imaging Assay Using CellomicsTM ArrayScan VTI Platform

                Catherine Bardelle and Joanna Boros

     

    6. Image-Based High Content Screening: Automating the Quantification Process for DNA Damage-Induced Foci

                Yi Chieh Lim

     

    7. Analyzing ATM Function by Electroporation of Endonucleases and Immunofluorescence Microscopy

                Keiji Suzuki

     

    8. Quantitative and Dynamic Imaging of ATM Kinase Activity by Bioluminescence Imaging

                Shyam Nyati, Grant Young, Brian Dale Ross, and Alnawaz Rehemtulla

     

    9. Zn(II)–Phos-Tag SDS-PAGE for Separation and Detection of a DNA Damage-Related Signaling Large Phosphoprotein

                Eiji Kinoshita, Emiko Kinoshita-Kikuta, and Tohru Koike

     

    10. Identification of ATM Protein Kinase Phosphorylation Sites by Mass Spectrometry

                Mark E. Graham, Martin F. Lavin, and Sergei V. Kozlov

     

    11. Studies of ATM Kinase Activity Using Engineered ATM Sensitive to ATP Analogues (ATM-AS)

                Masato Enari, Yuko Matsushima-Hibiya, Makoto Miyazaki, and Ryo Otomo

     

    12. Functional Characterization of ATM Kinase Using Acetylation-Specific Antibodies

                Sun Yingli and Du Fengxia

     

    13. Identification of ATM-Interacting Proteins by Co-Immunoprecipitation and Glutathione-S-Transferase (GST) Pull-Down Assays

                Amanda L. Bain, Janelle L. Harris, and Kum Kum Khanna

     

    14. ATM Activation and H2AX Phosphorylation Induced by Genotoxic Agents Assessed by Flow- and Laser Scanning-Cytometry

                Hong Zhao, H. Dorota Halicka, Jorge Garcia, Jiangwei Li, and Zbigniew Darzynkiewicz

     

    15. Peptide Immunoaffinity Enrichment with Targeted Mass Spectrometry: Application to Quantification of ATM Kinase Phospho-Signaling

                Jeffrey R. Whiteaker, Lei Zhao, Regine M. Schoenherr, Jacob J. Kennedy, Richard G. Ivey, and Amanda G. Paulovich

     

    16. Mass Spectrometry-Based Proteomics for Quantifying DNA Damage-Induced Phosphorylation

                Marina E. Borisova, Sebastian A. Wagner, and Petra Beli

     

    17. Statistical Analysis of ATM-Dependent Signaling in Quantitative Mass Spectrometry Phosphoproteomics

                Ashley J. Waardenberg

     

    18. ChIP Technique to Study Protein Dynamics at Defined DNA Double-Strand Breaks

                Jie Wen and Patrick Concannon

     

    19. Studies of the DNA Damage Response by Using the Lac Operator/Repressor (LacO/LacR) Tethering System

                Rossana Piccinno, Marta Cipinska, and Vassilis Roukos

     

    20. Imaging of Fluorescently-Tagged ATM Kinase at the Sites of DNA Double-Strand Breaks

                Anthony J. Davis, Shih-Ya Wang, David J. Chen, and Benjamin P.C. Chen

     

    21. Live Cell Imaging to Study Real-Time ATM-Mediated Recruitment of DNA Repair Complexes to Sites of Ionizing Radiation-Induced DNA Damage

                Burkhard Jakob and Gisela Taucher Scholz

     

    22. Analyzing Heterochromatic DNA Double Strand Break (DSB) Repair in Response to Ionizing Radiation

                Karolin Klement and Aaron A. Goodarzi

     

    23. Phenotypic Analysis of ATM Protein Kinase in DNA Double-Strand Break Formation and Repair

                Elisabeth Mian and Lisa Wiesmüller

     

    24. Monitoring DNA Repair Consequences of ATM Signaling Using Simultaneous Fluorescent Readouts

                Adrian Wiegmans

     

    25. Non-Canonical ATM Activation and Signaling in Response to Transcription-Blocking DNA Damage

                Jurgen A. Marteijn, Wim Vermeulen, and Maria Tresini

     

    26. Study of ATM Phosphorylation by Cdk5 in Neuronal Cells

                Hua She and Zixu Mao

     

    27. DNA Damage Response in Human Stem Cells and Neural Descendants

                Jason M. Beckta, Bret R. Adams, and Kristoffer Valerie

     

    28. A Patient-Specific Stem Cell Model to Investigate the Neurological Phenotype Observed in Ataxia-Telangiectasia

                Romal Stewart, Gautam Wali, Chris Perry, Martin Lavin, Francois Féron, Alan Mackay-Sim, and Ratneswary Sutharsan

     

    29. Lentiviral Reprogramming of A-T Patient Fibroblasts to Induced Pluripotent Stem Cells

                Sam Nayler, Sergei Kozlov, Martin Lavin, and Ernst Wolvetang

     

    30. Monitoring the ATM-Mediated DNA Damage Response in the Cerebellum Using Organotypic Cultures

                Efrat Tal and Yosef Shiloh