Allosteric Modulation for Drug Discovery
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A bridge for industrial and academic collaborations, this book overviews the concepts and therapeutic application of allosteric modulation to control protein function - explaining why it has gained strong momentum in drug discovery, technologies and methodologies to discover allosteric modulators, and allosteric modulator compounds. - Collects into one single resource the details on allosteric modulation of key drug targets, making for an encyclopedic coverage from basics to drug discovery applications - Describes methods to detect and analyze allosterism - Lets readers compare how allosteric ...
A bridge for industrial and academic collaborations, this book overviews the concepts and therapeutic application of allosteric modulation to control protein function - explaining why it has gained strong momentum in drug discovery, technologies and methodologies to discover allosteric modulators, and allosteric modulator compounds. - Collects into one single resource the details on allosteric modulation of key drug targets, making for an encyclopedic coverage from basics to drug discovery applications - Describes methods to detect and analyze allosterism - Lets readers compare how allosteric modulators function and used across different platforms - Includes the major drug target classes with demonstrated allosteric modulation - Features a companion website with color images and protocols that readers can access
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